| Type | Description |
|---|---|
| Definition | zinc finger protein 185 with LIM domain |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 11:37:00 | These data highlight the involvement of ZNF185 and cytoskeleton changes in p53-mediated cellular response to genotoxic stress and indicate ZNF185 as potential biomarker for epithelial cancer diagnosis. | 30446632 |
| 2019-05-18 11:08:00 | Results provide evidence that ZNF185 is a key component of the p63-dependent transcriptional program for stratified epithelial development and tissue homeostasis. ZNF185 deregulation, beyond deregulating cell adhesion in general, is also relevant for carcinoma formation of the stratified epithelia suggesting that ZNF185 may be a potential biomarker for squamous cell carcinoma diagnosis and prognosis. | 30337687 |
| 2017-07-01 11:35:00 | ZNF185 was mainly distributed in the cytoplasm of Leydig cells and Sertoli cells, as well as the head and tail of sperm cells. | 27667456 |
| 2017-02-04 12:30:00 | ZNF185 expression was significantly downregulated in lung adenocarcinoma tissues compared with the adjacent non-cancerous tissues and negatively correlated with lymphatic metastasis. ZNF185 overexpression inhibits the growth and invasion of LAC cells through inhibition of the AKT/GSK3beta signaling. | 27655485 |
| 2010-01-21 00:00:00 | transcriptional activation of ZNF185 and CYP3A4 is mediated by direct association of BRG1 with their promoters and a decreased level of ZNF185 is a common feature of lung tumours | 15731117 |
| Type | IDs |
|---|---|
| Synonymous | SCELL |
| Gene |
UniProtKB-ID:
ZN185_HUMAN,
B3KPM4_HUMAN
UniprotKB:
O15231,
B3KPM4
UniParc:
UPI00017A74DD,
UPI00001AF1FC,
UPI0001895B93,
UPI0001D27F7F,
UPI0000EE78D2,
UPI00015294FA,
UPI0000140358,
UPI0001D27F80,
UPI0001895B94,
UPI0001D27F7E
EMBL:
DQ508025,
AK296967,
DQ508026,
AK056517,
DQ508024,
U82671,
CH471172,
AK301530,
DQ508022,
Y09538,
AK095258,
AY997296,
DQ508023
Ensembl:
ENSG00000147394
KO:
hsa:7739
|
| Nucleutide sequences |
EMBL-CDS:
ABF57661.1,
ABF57660.1,
AAY54245.1,
BAH13507.1,
CAA70733.1,
BAC04511.1,
EAW72895.1,
BAG59511.1,
ABF57658.1,
ABF57659.1,
ABF57657.1,
EAW72893.1,
BAG51736.1
Gene_ORFName:
hCG_39570
Ensembl_TRS:
ENST00000370268,
ENST00000539731,
ENST00000449285,
ENST00000370270,
ENST00000454925,
ENST00000324823,
ENST00000318504,
ENST00000535861,
ENST00000318529
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000325307,
ENSP00000440847,
ENSP00000359293,
ENSP00000359291,
ENSP00000444367,
ENSP00000313919,
ENSP00000395228,
ENSP00000312782,
ENSP00000392984
RefSeq:
NP_001171578.1,
XP_016885316.1,
NP_001171580.1,
XP_016885323.1,
XP_016885311.1,
XP_005274799.1,
XP_005274798.1,
XP_016885313.1,
XP_016885318.1,
XP_005274795.1,
XP_005274797.1,
NP_009081.2,
NP_001375361.1,
NP_001171579.1,
XP_016885324.1,
XP_016885314.1,
XP_005274802.1,
XP_011529496.1,
NP_001171584.1,
XP_005274792.1,
NP_001171581.1,
XP_016885322.1,
XP_005274803.1,
XP_016885319.1,
XP_016885315.1,
XP_016885321.1,
XP_005274801.1,
XP_016885310.1,
XP_016885312.1,
XP_016885320.1,
XP_016885317.1,
XP_011529497.1,
XP_005274787.1,
NP_001171586.1,
NP_001171577.1,
XP_005274788.1
|
| Others |
UniRef100:
UniRef100_B3KPM4,
UniRef100_O15231
UniRef90:
UniRef90_G1RUY5,
UniRef90_O15231
UniRef50:
UniRef50_O15231
UniGene:
Hs.16622
CCDS:
CCDS55530.1,
CCDS69832.1,
CCDS55532.1,
CCDS48184.1,
CCDS55529.1,
CCDS55528.1,
CCDS55531.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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