| Type | Description |
|---|---|
| Definition | ankyrin repeat domain 11 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-22 10:45:00 | Ankrd11 knockdown delayed radial migration of cortical neurons. ANKRD11-deficient neurons displayed markedly reduced dendrite growth and branching as well as abnormal dendritic spine morphology. Ankrd11 knockdown suppressed acetylation of epigenetic molecules such as p53 and Histone H3. Furthermore, the mRNA levels of Trkb, Bdnf, and neurite growth-related genes were downregulated in ANKRD11-deficient cortical neurons. | 29274743 |
| 2015-04-18 10:56:00 | ANKRD11 C-terminus plays an important role in regulating the abundance of the protein, and a disturbance of the protein abundance due to the mutations leads to KBG syndrome. | 25413698 |
| 2010-01-21 00:00:00 | A Glu->Lys missense mutation in a highly conserved region causes osteopenia and craniofacial abnormalities. Homozygosity causes embryo death. Ankrd11 is a genetic regular of bone homeostasis. | 17986521 |
| Type | IDs |
|---|---|
| Synonymous | 2410104C19Rik, 3010027A04Rik, 6330578C09Rik, 9530048I21Rik, AA930108, Gm176, Yod |
| Gene |
UniProtKB-ID:
ANR11_MOUSE
UniprotKB:
E9Q4F7
UniParc:
UPI0000605E52
EMBL:
BC059876,
BC158043,
AC132287
Ensembl:
ENSMUSG00000035569
KO:
mmu:77087
|
| Nucleutide sequences |
EMBL-CDS:
AAH59876.1,
AAI58044.1
Ensembl_TRS:
ENSMUST00000098334
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000095939
RefSeq:
XP_030099711.1,
NP_001074848.2,
XP_030099712.1,
XP_036010270.1
|
| Others |
UniRef100:
UniRef100_E9Q4F7
UniRef90:
UniRef90_E9Q4F7
UniRef50:
UniRef50_Q6UB99
UniGene:
Mm.31567
CCDS:
CCDS40507.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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