| Type | Description |
|---|---|
| Definition | zinc finger protein 148 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:05:00 | ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway. | 31874246 |
| 2020-04-25 10:16:00 | Here, we show that succinate accumulation induced by SDHB loss of function increased the expression of zinc finger protein 148 (ZNF148, also named ZBP-89) in astrointestinal stromal tumor (GIST) cells. Meanwhile, ZNF148 is found to be phosphorylated by ERK at Ser306, and this phosphorylation results in ZNF148 binding to Forkhead box M1 (FOXM1) | 32060966 |
| 2019-03-23 12:14:00 | ZNF148(FL) could increase proliferation, invasion, and migration of colorectal cancer cells, while ZNF148(DeltaN) showed opposite effect; the two splicing isoforms of ZNF148 may exert a mutual antagonistic effect to each other on the malignant biological activities. | 30463804 |
| 2019-03-16 12:28:00 | Downregulation of ZNF148 drives the formation of a muscle phenotype with rapid expression of myosin heavy chain, even in proliferative conditions. This phenotype was most likely mediated by the robust and swift upregulation of MYOD and MEF2C. | 28811660 |
| 2019-03-09 12:25:00 | ZBP-89 is a potential tumor suppressor in hepatocellular carcinoma (HCC) and it can inhibit the growth of HCC via multiple channels; higher expression of ZBP-89 may predict better survivals and lower recurrence of HCC patients | 30142986 |
| Type | IDs |
|---|---|
| Synonymous | BERF-1, BFCOL1, GDACCF, HT-BETA, ZBP-89, ZFP148, pHZ-52 |
| Gene |
UniProtKB-ID:
ZN148_HUMAN
UniprotKB:
Q9UQR1
UniParc:
UPI00001BDA60,
UPI000013C2FF
EMBL:
AF039019,
AJ236885,
BC050260,
BC018971,
U96633,
CH471052,
AC108688
Ensembl:
ENSG00000163848
KO:
hsa:7707
|
| Nucleutide sequences |
EMBL-CDS:
EAW79395.1,
EAW79396.1,
AAH50260.1,
AAB57692.1,
EAW79398.1,
CAA15422.1,
AAH18971.1,
AAC39926.1,
EAW79394.1
Ensembl_TRS:
ENST00000485866,
ENST00000360647,
ENST00000492394,
ENST00000484491
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000420448,
ENSP00000419322,
ENSP00000353863,
ENSP00000420335
RefSeq:
NP_001335361.1,
NP_001335365.1,
NP_001335362.1,
NP_001335357.1,
NP_001335363.1,
NP_001335359.1,
NP_001335353.1,
NP_001335358.1,
NP_001335356.1,
NP_068799.2,
NP_001335360.1,
NP_001335355.1,
NP_001335354.1
|
| Others |
UniRef100:
UniRef100_Q9UQR1
UniRef90:
UniRef90_Q9UQR1
UniRef50:
UniRef50_Q9UQR1
UniGene:
Hs.592591
CCDS:
CCDS3031.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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