Type | Description |
---|---|
Definition | lysine (K)-specific demethylase 8 |
Date | Results | Publications |
---|---|---|
2019-03-09 12:34:00 | we report sustained Schwann cell proliferation caused by an increased expression of the direct Miz1 target gene Kdm8, encoding a H3K36me2 demethylase | 29217679 |
2018-06-30 11:18:00 | The protease activities of JMJD5 and JMJD7 represent a mechanism for removal of histone tails bearing methylated arginine residues and define a potential mechanism of transcription regulation. | 28847961 |
2016-11-19 10:35:00 | Jmjd5 is involved in the transcriptional regulation of a subset of p53-regulated genes, possibly through the control of p53 recruitment at the gene loci. | 26334721 |
2016-08-06 10:52:00 | Data suggest that Jmjd5 partially accumulates on mitotic spindles during mitosis; depletion of Jmjd5 results in significant mitotic arrest, spindle assembly defects, and sustained activation of spindle assembly checkpoint. | 26710852 |
2012-05-19 11:14:00 | Collectively, these data indicate that JMJD5 is essential during embryonal development and a repressor of p53 expression. The latter suggests that JMJD5 has oncogenic activity and accordingly JMJD5 is upregulated in leukemias and breast cancer. | 22402282 |
Type | IDs |
---|---|
Synonymous | 3110005O21Rik, Jmjd5 |
Gene |
UniProtKB-ID:
KDM8_MOUSE
UniprotKB:
Q9CXT6
UniParc:
UPI00000235C2
EMBL:
AK014006,
BC024807
Ensembl:
ENSMUSG00000030752
KO:
mmu:77035
|
Nucleutide sequences |
EMBL-CDS:
BAB29111.1,
AAH24807.1
Ensembl_TRS:
ENSMUST00000033010
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033010
RefSeq:
NP_084118.1,
XP_017167873.1
|
Others |
UniRef100:
UniRef100_Q9CXT6
UniRef90:
UniRef90_Q9CXT6
UniRef50:
UniRef50_Q9CXT6
UniGene:
Mm.307239
CCDS:
CCDS21821.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员