| Type | Description |
|---|---|
| Definition | lysine (K)-specific demethylase 8 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 12:34:00 | we report sustained Schwann cell proliferation caused by an increased expression of the direct Miz1 target gene Kdm8, encoding a H3K36me2 demethylase | 29217679 |
| 2018-06-30 11:18:00 | The protease activities of JMJD5 and JMJD7 represent a mechanism for removal of histone tails bearing methylated arginine residues and define a potential mechanism of transcription regulation. | 28847961 |
| 2016-11-19 10:35:00 | Jmjd5 is involved in the transcriptional regulation of a subset of p53-regulated genes, possibly through the control of p53 recruitment at the gene loci. | 26334721 |
| 2016-08-06 10:52:00 | Data suggest that Jmjd5 partially accumulates on mitotic spindles during mitosis; depletion of Jmjd5 results in significant mitotic arrest, spindle assembly defects, and sustained activation of spindle assembly checkpoint. | 26710852 |
| 2012-05-19 11:14:00 | Collectively, these data indicate that JMJD5 is essential during embryonal development and a repressor of p53 expression. The latter suggests that JMJD5 has oncogenic activity and accordingly JMJD5 is upregulated in leukemias and breast cancer. | 22402282 |
| Type | IDs |
|---|---|
| Synonymous | 3110005O21Rik, Jmjd5 |
| Gene |
UniProtKB-ID:
KDM8_MOUSE
UniprotKB:
Q9CXT6
UniParc:
UPI00000235C2
EMBL:
AK014006,
BC024807
Ensembl:
ENSMUSG00000030752
KO:
mmu:77035
|
| Nucleutide sequences |
EMBL-CDS:
BAB29111.1,
AAH24807.1
Ensembl_TRS:
ENSMUST00000033010
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033010
RefSeq:
NP_084118.1,
XP_017167873.1
|
| Others |
UniRef100:
UniRef100_Q9CXT6
UniRef90:
UniRef90_Q9CXT6
UniRef50:
UniRef50_Q9CXT6
UniGene:
Mm.307239
CCDS:
CCDS21821.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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