| Type | Description |
|---|---|
| Definition | polycomb group ring finger 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-17 11:17:00 | Low expression of Mel-18 is correlated with gastric cancer. | 27542229 |
| 2016-09-10 12:06:00 | Suggest a novel role of PCGF2 in arsenic trioxide-mediated degradation of PML-RARA that PCGF2 might act as a negative regulator of UBE2I via direct interaction. | 27030546 |
| 2015-08-22 10:30:00 | Mel-18 underexpression in luminal breast cancer cells caused ER-alpha downregulation.Its overexpression restored it in triple-negative breast cancer cells. MEL-18 suppressed SUMOylation of the ESR1 transactivators p53 and SP1. | 25822021 |
| 2015-01-10 11:01:00 | It was therefore concluded that the lower Mel-18 expression might contribute to colorectal cancer development/progression. | 24964959 |
| 2014-05-03 10:56:00 | Mel-18 functions as a tumor suppressor by its novel negative control of the epithelial-mesenchymal transition in breast cancer. | 23474752 |
| Type | IDs |
|---|---|
| Synonymous | MEL-18, RNF110, ZNF144 |
| Gene |
UniProtKB-ID:
PCGF2_HUMAN,
A0A024R1V6_HUMAN
UniprotKB:
P35227,
A0A024R1V6
UniParc:
UPI0000001279
EMBL:
BC024255,
BC004858,
AC006449,
BX647429,
CH471152,
D13969
Ensembl:
ENSG00000277258,
ENSG00000278644
KO:
hsa:7703
|
| Nucleutide sequences |
EMBL-CDS:
AAH24255.1,
AAH04858.1,
EAW60528.1,
BAA03074.1,
EAW60529.1
Gene_ORFName:
hCG_31397
Ensembl_TRS:
ENST00000611883,
ENST00000631610,
ENST00000620225,
ENST00000631566,
ENST00000616199,
ENST00000610440
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000478970,
ENSP00000488872,
ENSP00000482815,
ENSP00000478517,
ENSP00000488868,
ENSP00000482063
RefSeq:
XP_005257697.1,
XP_016880505.1,
NP_009075.1,
NP_001356544.1,
NP_001356543.1
|
| Others |
UniRef100:
UniRef100_P35227
UniRef90:
UniRef90_P35227
UniRef50:
UniRef50_P35227
UniGene:
Hs.371617,
Hs.713595
CCDS:
CCDS32638.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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