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76967 2700049A03Rik

76967

2700049A03Rik

RIKEN cDNA 2700049A03 gene

protein-coding

Mus musculus

基因描述

Type Description
Definition RIKEN cDNA 2700049A03 gene

研究结论

Date Results Publications
2020-04-18 12:40:00 Findings in a mouse model reveal a role for Talpid3 in granule precursor cell migration in the cerebellum (either direct or indirect) which together with defective Hedgehog signaling underlies the Joubert syndrome phenotype. 30924151
2017-10-14 10:26:00 Gli2 and Gli3 are dephosphorylated and activated in cilia and that impaired Gli2 and Gli3 processing in Ta3 mutant is at least in part due to a decrease in Gli2 and Gli3 phosphorylation. 28673820
2015-06-20 11:20:00 The loss of Talpid3-binding centrosomal protein Cep120 results in failed centriole duplication and consequently ciliogenesis, which together underlie Cep120 mutant cerebellar hypoplasia. 25251415
2011-09-24 11:47:00 Data show that talpid3-/- mouse embryos lack primary cilia and, like talpid(3) chicken embryos, have face and neural tube defects but also defects in left/right asymmetry. 21750036

名称对应

Type IDs
Synonymous Ta3, Talpid3, mKIAA0586
Gene
UniProtKB-ID: TALD3_MOUSE, E9Q0E2_MOUSE
UniprotKB: E9PV87, E9Q0E2
UniParc: UPI0000429289, UPI0001B02684
EMBL: BC150744, AC159620
Ensembl: ENSMUSG00000034601
KO: mmu:76967
Nucleutide sequences
EMBL-CDS: AAI50745.1
Ensembl_TRS: ENSMUST00000149564, ENSMUST00000045907
Protein sequencees
Ensembl_PRO: ENSMUSP00000118956, ENSMUSP00000044701
RefSeq: XP_006516429.1, NP_084094.1, XP_006516427.1, NP_001156850.1, XP_030102838.1, XP_006516428.1
Others
UniRef100: UniRef100_E9PV87, UniRef100_E9Q0E2
UniRef90: UniRef90_E9PV87
UniRef50: UniRef50_Q9BVV6
UniGene: Mm.87290
CCDS: CCDS49081.1

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