Type | Description |
---|---|
Definition | BICD cargo adaptor 2 |
Date | Results | Publications |
---|---|---|
2021-01-16 15:58:00 | Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy. | 32183910 |
2020-07-18 10:53:00 | Findings demonstrate a novel, cell-intrinsic role of BICD2 in cortical neuron migration in vivo and provide new insights into BICD2-dependent dynein-mediated functions during cortical development. | 31655624 |
2017-08-12 10:16:00 | Data suggest that binding of Lis1 to DDB complex does not strongly disrupt processive motility along microtubules; motile DDB complex binds up to two Lis1 dimers; mutational analysis suggested that Lis1 binds directly to the dynein motor domains during DDB complex movement. (Lis1 = lissencephaly 1 protein; DDB complex = dynein-dynactin-BicD2 complex; BicD2 = bicaudal D homolog 2 protein) | 28576829 |
2015-12-05 11:10:00 | several analyses of vesicular transport demonstrated that Rab6A and BICD2 play crucial roles in Golgi tubule fusion with the endoplasmic reticulum (ER) in brefeldin A (BFA)-treated cells | 25962623 |
2014-12-06 11:27:00 | Data indicate that Bicaudal-D2 (BICD2)-deficient mice develop disrupted laminar organization of cerebral cortex and the cerebellum, pointing to impaired radial neuronal migration. | 24614806 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
BICD2_MOUSE,
D3Z390_MOUSE
UniprotKB:
Q921C5,
D3Z390
UniParc:
UPI000068813B,
UPI00000E6F57,
UPI00001BBAF3,
UPI00001BBAF2
EMBL:
AK122348,
AC132245,
AK002683,
BC032198,
AJ250106,
AK003456
Ensembl:
ENSMUSG00000037933
KO:
mmu:76895
|
Nucleutide sequences |
EMBL-CDS:
AAH32198.1,
BAC25035.1,
BAC65630.1,
BAB22282.1,
CAC51393.1
Ensembl_TRS:
ENSMUST00000048544,
ENSMUST00000110085,
ENSMUST00000110084
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039394,
ENSMUSP00000105712,
ENSMUSP00000105711
RefSeq:
NP_001034268.1,
NP_084067.1,
XP_011242731.1,
NP_001034269.1
|
Others |
UniRef100:
UniRef100_Q921C5
UniRef90:
UniRef90_Q921C5
UniRef50:
UniRef50_Q8TD16
UniGene:
Mm.197387
CCDS:
CCDS36657.1,
CCDS36656.1
|
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