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76895 Bicd2

76895

Bicd2

BICD cargo adaptor 2

protein-coding

Mus musculus

基因描述

Type Description
Definition BICD cargo adaptor 2

研究结论

Date Results Publications
2021-01-16 15:58:00 Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy. 32183910
2020-07-18 10:53:00 Findings demonstrate a novel, cell-intrinsic role of BICD2 in cortical neuron migration in vivo and provide new insights into BICD2-dependent dynein-mediated functions during cortical development. 31655624
2017-08-12 10:16:00 Data suggest that binding of Lis1 to DDB complex does not strongly disrupt processive motility along microtubules; motile DDB complex binds up to two Lis1 dimers; mutational analysis suggested that Lis1 binds directly to the dynein motor domains during DDB complex movement. (Lis1 = lissencephaly 1 protein; DDB complex = dynein-dynactin-BicD2 complex; BicD2 = bicaudal D homolog 2 protein) 28576829
2015-12-05 11:10:00 several analyses of vesicular transport demonstrated that Rab6A and BICD2 play crucial roles in Golgi tubule fusion with the endoplasmic reticulum (ER) in brefeldin A (BFA)-treated cells 25962623
2014-12-06 11:27:00 Data indicate that Bicaudal-D2 (BICD2)-deficient mice develop disrupted laminar organization of cerebral cortex and the cerebellum, pointing to impaired radial neuronal migration. 24614806

名称对应

Type IDs
Gene
UniProtKB-ID: BICD2_MOUSE, D3Z390_MOUSE
UniprotKB: Q921C5, D3Z390
UniParc: UPI000068813B, UPI00000E6F57, UPI00001BBAF3, UPI00001BBAF2
EMBL: AK122348, AC132245, AK002683, BC032198, AJ250106, AK003456
Ensembl: ENSMUSG00000037933
KO: mmu:76895
Nucleutide sequences
EMBL-CDS: AAH32198.1, BAC25035.1, BAC65630.1, BAB22282.1, CAC51393.1
Ensembl_TRS: ENSMUST00000048544, ENSMUST00000110085, ENSMUST00000110084
Protein sequencees
Ensembl_PRO: ENSMUSP00000039394, ENSMUSP00000105712, ENSMUSP00000105711
RefSeq: NP_001034268.1, NP_084067.1, XP_011242731.1, NP_001034269.1
Others
UniRef100: UniRef100_Q921C5
UniRef90: UniRef90_Q921C5
UniRef50: UniRef50_Q8TD16
UniGene: Mm.197387
CCDS: CCDS36657.1, CCDS36656.1

全选

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研究热度

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