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76884 Cyfip2

76884

Cyfip2

cytoplasmic FMR1 interacting protein 2

protein-coding

Mus musculus

基因描述

Type Description
Definition cytoplasmic FMR1 interacting protein 2

研究结论

Date Results Publications
2021-03-06 13:32:00 Molecular Dissection of Neurodevelopmental Disorder-Causing Mutations in CYFIP2. 32486060
2021-02-13 13:25:00 Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain. 32560809
2021-01-09 13:30:00 Haploinsufficiency of Cyfip2 Causes Lithium-Responsive Prefrontal Dysfunction. 32562430
2018-04-07 10:42:00 Study characterized the functional roles of the two brain-specific phosphorylation sites (S582 and T1067) of CYFIP2 in cultured hippocampal neurons; found that overexpression of the phospho-blocking T1067A mutant significantly decreased the density of stubby spines, but not other types of spines. Study found that T1067 phosphorylation of CYFIP2 could potentially weaken the interaction between CYFIP2 and Nap1. 28692454
2017-08-19 11:55:00 Study identified cytoplasmic FMR1-Interacting Protein 2 (Cyfip2) as a major significant genetic factor underlying binge eating and provide a behavioral paradigm for future genome-wide association studies in populations with increased genetic complexity. 27914629

名称对应

Type IDs
Synonymous 1500004I01Rik, 6430511D02Rik, AA930218, AU022376, Pir121, mKIAA1168
Gene
UniProtKB-ID: CYFP2_MOUSE, Q6PGK0_MOUSE
UniprotKB: Q5SQX6, Q6PGK0
UniParc: UPI00001E58FD, UPI00001CDE4D
EMBL: AF334144, AL662806, AK147586, AK030397, AK147224, AL713958, AF162472, BC056974, AB093288, AK147632
Ensembl: ENSMUSG00000020340
KO: mmu:76884
Nucleutide sequences
EMBL-CDS: AAD45803.1, BAC26942.1, AAK81821.1, BAC41472.2, BAE28036.1, BAE28010.1, BAE27779.1, AAH56974.1
Ensembl_TRS: ENSMUST00000093166, ENSMUST00000165599, ENSMUST00000093165
Protein sequencees
Ensembl_PRO: ENSMUSP00000090854, ENSMUSP00000090853, ENSMUSP00000127586
RefSeq: XP_036012977.1, XP_036012979.1, XP_006534524.1, NP_001239389.1, NP_598530.2, NP_001239388.1, XP_006534525.1, XP_036012978.1, XP_006534526.1
Others
UniRef100: UniRef100_Q6PGK0, UniRef100_Q5SQX6
UniRef90: UniRef90_Q5SQX6, UniRef90_Q6PGK0
UniRef50: UniRef50_Q7L576
UniGene: Mm.154358, Mm.454389
CCDS: CCDS24573.1

全选

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