| Type | Description |
|---|---|
| Definition | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| Date | Results | Publications |
|---|---|---|
| 2019-03-23 12:22:00 | Results found that runx1(W84X/W84X) mutation led to the reduction and disordering of B cells, as well as the failure of V(D)J rearrangements in B cells but not T cells, resulting in antibody-inadequate-mediated immunodeficiency. By contrast, T cell development was not affected. Furthermore, an evolutionarily conserved function of runx1 was demonstrated in maturation and differentiation of B cells in adult zebrafish. | 30045885 |
| Type | IDs |
|---|---|
| Synonymous | MTG8, si:ch211-232j17.1, wu:fi14b07, zgc:154044 |
| Gene |
UniProtKB-ID:
A0A0R4IXV4_DANRE,
E9QDS4_DANRE,
Q1L8K2_DANRE
UniprotKB:
A0A0R4IXV4,
E9QDS4,
Q1L8K2
UniParc:
UPI0000D71E93,
UPI00062E2547,
UPI0007EEACA5
EMBL:
CT027830,
CR735113,
CR759910
Ensembl:
ENSDARG00000003680
KO:
dre:767809
|
| Nucleutide sequences |
Ensembl_TRS:
ENSDART00000162517,
ENSDART00000010294,
ENSDART00000147226
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000139489,
ENSDARP00000020377,
ENSDARP00000123046
RefSeq:
XP_017207763.1,
XP_017207764.1,
NP_001070244.2,
XP_017207765.1
|
| Others |
UniRef100:
UniRef100_A0A0R4IXV4,
UniRef100_E9QDS4,
UniRef100_Q1L8K2
UniRef90:
UniRef90_Q61909,
UniRef90_Q1L8K2,
UniRef90_A0A0R4IXV4
UniRef50:
UniRef50_A0A3Q2GVI8,
UniRef50_Q61909,
UniRef50_Q06455
UniGene:
Dr.148641
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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