| Type | Description |
|---|---|
| Definition | sorting nexin family member 27 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:49:00 | Sorting nexin 27 (SNX27) variants associated with seizures, developmental delay, behavioral disturbance, and subcortical brain abnormalities. | 31721175 |
| 2020-09-26 13:05:00 | Characterization of the interaction between beta-catenin and sorting nexin 27: contribution of the type I PDZ-binding motif to Wnt signaling. | 31696214 |
| 2019-12-07 10:31:00 | Downregulation of SNX27 expression does not exacerbate amyloidogenesis in the APP/PS1 Alzheimer's disease mouse model. | 30797171 |
| 2019-07-13 12:59:00 | This study broadens our understanding of SNX27 as an integrator of lipid-based signals with the control of transcription and metabolic pathways. | 29180720 |
| 2018-01-06 11:45:00 | Results show a crucial role of SNX27 in modulating GPR17 levels by means of a post-translational mechanism and highlights the relationship between the trafficking of the receptor through the endomembrane system and oligodendrocyte differentiation; and provide novel evidence of impairment of GPR17 expression and oligodendrocyte maturation in a mouse model of Down syndrome that is characterized by SNX27 down-regulation. | 27270750 |
| Type | IDs |
|---|---|
| Synonymous | 5730552M22Rik, ESTM45, ESTM47, R75405 |
| Gene |
UniProtKB-ID:
SNX27_MOUSE
UniprotKB:
Q3UHD6
UniParc:
UPI00001C2CC9,
UPI00001F0853
EMBL:
AK147452,
AK122296,
BC053495,
AK017836
Ensembl:
ENSMUSG00000028136
KO:
mmu:76742
|
| Nucleutide sequences |
EMBL-CDS:
BAC65578.1,
BAB30966.1,
BAE27921.1,
AAH53495.1
Ensembl_TRS:
ENSMUST00000029783,
ENSMUST00000107283
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000102904,
ENSMUSP00000029783
RefSeq:
XP_006502321.1,
NP_083997.1,
XP_030108737.1,
NP_001075953.1,
XP_030108736.1
|
| Others |
UniRef100:
UniRef100_Q3UHD6
UniRef90:
UniRef90_Q8K4V4
UniRef50:
UniRef50_Q8K4V4
UniGene:
Mm.28160
CCDS:
CCDS38537.1,
CCDS38538.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员