| Type | Description |
|---|---|
| Definition | protein phosphatase 1, regulatory inhibitor subunit 11 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 10:13:00 | The three regulators (PPP1R2, PPP1R7, and PPP1R11)share localization with PP1gamma2 in the head and the principal piece of sperm. We show that the association of inhibitors to PP1gamma2 changes during epididymal sperm maturation. In immotile caput epididymal sperm, PPP1R2 and PPP1R7 are not bound to PP1gamma2, whereas in motile caudal sperm, all three inhibitors are bound as heterodimers or heterotrimers. | 30144392 |
| 2017-11-26 00:16:00 | Lentiviral gene transfer or knockdown of PPP1R11 in mouse lungs significantly affects lung inflammation and the clearance of Staphylococcus aureus. There is a negative correlation between PPP1R11 and TLR2 levels in white blood cell samples isolated from patients with Staphylococcus aureus infections. | 27805901 |
| 2010-01-21 00:00:00 | Tctex5 might be a specific protein phosphatase-1 inhibitor in sperm; various Tctex5 transcripts and isoforms and cellular locations imply its different roles in spermatogenesis. | 17342733 |
| 2010-01-21 00:00:00 | Data show a reciprocal relationship between protein phosphatase isoform PP1gamma2 and its regulator PPP1R11, and suggest that complex formation between them in testis may prevent proteolysis of PPP1R11 and germ cell apoptosis. | 19300506 |
| Type | IDs |
|---|---|
| Synonymous | 1500041B02Rik, AV117883, Hcgv, Tcte5, Tctex-5, Tctex5 |
| Gene |
UniProtKB-ID:
PP1RB_MOUSE,
A5A4Y9_MOUSE
UniprotKB:
Q8K1L5,
A5A4Y9
UniParc:
UPI00000E886B,
UPI0000024E27
EMBL:
AK089107,
AK170104,
EF528576,
CR956641,
AK005379,
BC027737
Ensembl:
ENSMUSG00000036398
KO:
mmu:76497
|
| Nucleutide sequences |
EMBL-CDS:
BAE41566.1,
AAH27737.1,
BAC40754.1,
BAB23986.1,
ABP88916.1
Ensembl_TRS:
ENSMUST00000174711,
ENSMUST00000040402
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000134685,
ENSMUSP00000047202
RefSeq:
NP_083908.1
|
| Others |
UniRef100:
UniRef100_A5A4Y9,
UniRef100_Q8K1L5
UniRef90:
UniRef90_Q8K1L5
UniRef50:
UniRef50_O60927
UniGene:
Mm.46176
CCDS:
CCDS28729.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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