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76464 Knl1

76464

Knl1

kinetochore scaffold 1

protein-coding

Mus musculus

基因描述

Type Description
Definition kinetochore scaffold 1

研究结论

Date Results Publications
2019-07-13 11:14:00 Study in mouse model finds that following Knl1 deletion, segregation errors in mitotic neural progenitor cells give rise to DNA damage on the missegregated chromosomes. This triggers rapid p53 activation and robust apoptotic and microglial phagocytic responses that extensively eliminate cells with somatic genome damage, thus causing microcephaly. 31197172

名称对应

Type IDs
Synonymous 2310043D08Rik, 5730505K17Rik, Casc5
Gene
UniProtKB-ID: A3KGI3_MOUSE
UniprotKB: A3KGI3
UniParc: UPI0000D65C63
EMBL: AL772264
Ensembl: ENSMUSG00000027326
Nucleutide sequences
Ensembl_TRS: ENSMUST00000028802, ENSMUST00000099542
Protein sequencees
Ensembl_PRO: ENSMUSP00000097140, ENSMUSP00000028802
RefSeq: XP_006500439.1, XP_006500440.1, NP_083893.2, NP_001349661.1
Others
UniRef100: UniRef100_A3KGI3
UniRef90: UniRef90_A3KGI3
UniRef50: UniRef50_Q8NG31
UniGene: Mm.202518

全选

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研究热度

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