| Type | Description |
|---|---|
| Definition | dishevelled associated activator of morphogenesis 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 11:13:00 | we generated Daam-deficient mice by gene targeting and found that Daam1, but not Daam2, is necessary for fetal survival. Embryonic development of Daam1 mutants was delayed most likely due to functional defects in the labyrinthine layer of the placenta. Examination of Daam2 and Daam1/2 double mutants revealed that Daam1 and Daam2 are functionally redundant during placental development. | 32353019 |
| 2016-05-28 11:35:00 | Daam1 knockout mice that were also homozygous for Daam2 had stronger noncompaction cardiomyopathy, severely reduced cardiac function, disrupted sarcomere structure, and increased myocardial proliferation. | 26526197 |
| 2015-05-23 11:27:00 | a pharmacological strategy to inhibit Daam2-PIP5K function, application of which stimulates remyelination after white matter injury | 25754822 |
| 2010-01-21 00:00:00 | Daams are expressed in tissues known to require Wnts, so effectors of Wnt signaling during vertebrate development. | 15533824 |
| 2010-01-21 00:00:00 | involved in pivotal steps in neuronal cell differentiation and movement | 15464228 |
| Type | IDs |
|---|---|
| Synonymous | 2310016D11Rik, AI843643, AW557870 |
| Gene |
UniProtKB-ID:
DAAM2_MOUSE
UniprotKB:
Q80U19
UniParc:
UPI000017DEBD,
UPI0000355531
EMBL:
AY426536,
AC165258,
AC124748,
AK122266,
BC050043
Ensembl:
ENSMUSG00000040260
KO:
mmu:76441
|
| Nucleutide sequences |
EMBL-CDS:
BAC65548.2,
AAR05119.1,
AAH50043.1
Ensembl_TRS:
ENSMUST00000057610,
ENSMUST00000224595
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000153095,
ENSMUSP00000052085
RefSeq:
XP_036016721.1,
NP_001366300.1,
XP_006525148.1,
XP_006525153.1,
NP_001008232.2,
XP_036016720.1,
XP_006525152.1,
XP_006525149.1,
NP_001366301.1,
XP_006525147.1,
XP_036016719.1,
XP_006525146.1
|
| Others |
UniRef100:
UniRef100_Q80U19
UniRef90:
UniRef90_Q80U19
UniRef50:
UniRef50_Q80U19
UniGene:
Mm.211275
CCDS:
CCDS37648.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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