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76408 Abcc3

76408

Abcc3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

protein-coding

Mus musculus

基因描述

Type Description
Definition ATP-binding cassette, sub-family C (CFTR/MRP), member 3

研究结论

Date Results Publications
2017-12-02 11:11:00 Abbcc3 knock-out mice have enhanced platelet response to clopidogrel due to increased formation of clopidogral active metabolite. 27525577
2016-08-13 12:01:00 data show that this transporter activity is involved in ABCC3-induced senescence, demonstrating that this protein has a complex role in cancer, since its loss of function may promote escape from OIS and tumor formation 26073088
2012-08-11 10:59:00 Transport of cefadroxil by ABCC3 and ABCC4 was saturable with K(m) values of 2.5 +/- 0.7 and 0.25 +/- 0.07 mM, respectively. 22166395
2012-05-26 10:45:00 role of the bile acid membrane transporter Mrp3 (Abcc3), which is expressed in the liver and gut, in the hepatic growth response elicited by bile acids and in liver regeneration after partial hepatectomy 21756856
2012-05-05 11:17:00 Both Abcc2 and Abcc3 significantly influenced the PK properties of MTX. 21841039

名称对应

Type IDs
Synonymous 1700019L09Rik, ABC31, MLP2, MOAT-D, MRP3
Gene
UniProtKB-ID: MRP3_MOUSE, A0A0R4J015_MOUSE
UniprotKB: B2RX12, A0A0R4J015
UniParc: UPI000185D563, UPI0001747AC6, UPI00001E63D3, UPI00004FF915
EMBL: AY841885, AK155664, AL645965, BC048825, AY795569, AF534127, BC150788, AK149551, AF534128
Ensembl: ENSMUSG00000020865
KO: mmu:76408
Nucleutide sequences
EMBL-CDS: AAX39010.1, AAX33774.1, CAI25949.1, BAE33375.1, BAE28953.1, AAH48825.1, AAQ10531.1, AAI50789.1, AAQ10530.1
Ensembl_TRS: ENSMUST00000021231
Protein sequencees
Ensembl_PRO: ENSMUSP00000021231
RefSeq: NP_001350116.1, NP_001350118.1, NP_083876.3
Others
UniRef100: UniRef100_B2RX12, UniRef100_A0A0R4J015
UniRef90: UniRef90_B2RX12-2, UniRef90_O88563
UniRef50: UniRef50_O88563
UniGene: Mm.23942
CCDS: CCDS25254.1, CCDS88225.1

全选

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