Sun5 - Sad1 and UNC84 domain containing 5-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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76407 Sun5

基因描述

Type	Description
Definition	Sad1 and UNC84 domain containing 5

研究结论

Date	Results	Publications
2018-06-02 10:42:00	These studies reveal the essential role of SUN5 in anchoring sperm head to the tail and provide a promising way to treat this kind of acephalic spermatozoa-associated male infertility.	28945193
2016-02-06 10:14:00	In Dpy19l2 knock-out round spermatids, the detachment of the acrosome leads to Sun5 and lamin B1 relocalization, confirming that Sun5 protein is excluded from the nuclear envelope facing the acrosome.	25775128
2011-12-24 10:04:00	may play an important role in the meiotic stage of spermatogenesis	21711156
2011-10-03 15:33:00	and are transmembrane proteins that localize to the nuclear envelope.	21159740
2011-01-22 11:20:00	SRG4 was cloned into pUCm-T vectors and sequenced, subcloned into a prokaryotic expression vector and expression of induced by IPTG.	17618558

名称对应

Type	IDs
Synonymous	1700021O15Rik, SPAG4L-2, SRG4, Spag4l
Gene	UniProtKB-ID: SUN5_MOUSE, A0A0R4J084_MOUSE UniprotKB: Q9DA32, A0A0R4J084 UniParc: UPI000327BF24, UPI0000022BF7, UPI0001C08DBB EMBL: FJ667498, AY307077, AK006225, AL833803 Ensembl: ENSMUSG00000027480 KO: mmu:76407
Nucleutide sequences	EMBL-CDS: BAB24468.1, ACV74249.1, AAP69223.1 Ensembl_TRS: ENSMUST00000028982
Protein sequencees	Ensembl_PRO: ENSMUSP00000028982 RefSeq: XP_006500437.1, XP_011238140.1, XP_006500438.1, NP_083875.1, XP_030108049.1, XP_006500435.2, NP_001291977.1
Others	UniRef100: UniRef100_A0A0R4J084, UniRef100_Q9DA32 UniRef90: UniRef90_Q9DA32 UniRef50: UniRef50_Q9DA32 UniGene: Mm.33629

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29298896	Mechanistic insights into acephalic spermatozoa syndrome-associated mutations in the human SUN5 gene. J Biol Chem Yongliang Shang , Jie Yan , Wenhao Tang , Chao Liu , Sai Xiao , Yueshuai Guo , Li Yuan , Liang Chen , Hui Jiang , Xuejiang Guo , Jie Qiao , Wei Li	2018-02-16	-
28945193	Essential role for SUN5 in anchoring sperm head to the tail. Elife Yongliang Shang , Fuxi Zhu , Lina Wang , Ying-Chun Ouyang , Ming-Zhe Dong , Chao Liu , Haichao Zhao , Xiuhong Cui , Dongyuan Ma , Zhiguo Zhang , Xiaoyu Yang , Yueshuai Guo , Feng Liu , Li Yuan , Fei Gao , Xuejiang Guo , Qing-Yuan Sun , Yunxia Cao , Wei Li	2017-09-25	-
25775128	Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope. PLoS ONE Sandra Yassine , Jessica Escoffier , Roland Abi Nahed , Roland Abi Nahed , Virginie Pierre , Thomas Karaouzene , Pierre F Ray , Christophe Arnoult	2015-01-01	Dpy19l2, Sun5
21711156	SPAG4L, a novel nuclear envelope protein involved in the meiotic stage of spermatogenesis. DNA Cell Biol. Xian-Zhen Jiang , Ming-Gang Yang , Li-Hua Huang , Chang-Qi Li , Xiao-Wei Xing	2011-11-01	Sun5, SUN5
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21159740	SPAG4L/SPAG4L-2 are testis-specific SUN domain proteins restricted to the apical nuclear envelope of round spermatids facing the acrosome. Mol. Hum. Reprod. Cornelia Frohnert , Stephanie Schweizer , Sigrid Hoyer-Fender	2011-04-01	Sun5
17618558	[Prokaryotic expression and purification of SRG4, a novel mouse spermatogenesis gene]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Xiao-wei Xing , Hong Yuan , Wei Wang	2007-08-01	Sun5
17650487	[Expression of a novel spermatogenesis gene SRG4 in postpartum normal and cryptorchid mouse testis]. Yi Chuan Xiao-Wei Xing , Lu-Yun Li , Guang-Xiu Lu	2007-06-01	-
16141072	The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C SchÃ¶nbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)	2005-09-02	-
16141073	Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G EngstrÃ¶m , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium	2005-09-02	Gm14018, Gm14964, F630206G17Rik, Oog3, Notumos, Ldlrap1, Mdn1, Pydc3, 9330171B17Rik, Mfap1b, Tmsb15b2, Gm12802, E430020m11rik, Gm11335, Gm15772, Gm17762, A930017K11Rik, LOC100036513, Gata5os, Umad1, Gm16982, Gm9887, Gm9872, LOC100036530, Gm9934, Gm9913, Gm11149, BC028777, Gm13999, LOC100036540, Gm9744, Gm9983, D630002J18Rik, Gm16525, Gm11696, Dnajc3, 9430060I03Rik, Gm12359, 4921516A02Rik, Fam129c, Gm10589, Rsph3b, Rnaset2a, 5430403G19Rik, D030047H15Rik, Gm13274, B930046K06Rik, Gm10862, Gm10792, Gm10802, Gm10532, G730003C15Rik, Runx2os1, Gm15612, Gm10856, Gm10857, Gm10685, Gm10803, Gm10723, F630028O10Rik, Gm10836, Gm10405, Gm10513, Gm10609, F630201L12Rik, 4932427H20Rik, Zfp389, Gm10763, Gm10062, Gm10714, Gm10531, Gm10876, Gm10750, Gm10433, Gm10837, Gm10647, Gm10648, Gm10650, Gm10610, F830115B05Rik, Gm10473, Gm10614, Gm10286, G730046D07Rik, Gm10287, Gm10785, Gm10183, Gm10512, 1700061E17Rik, Gm44113, Gm10579, Gm10741, Gm10827, Gm10522, Gm10536, Gm15998, Faddos, D130050E23Rik, Gm10735

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