| Type | Description |
|---|---|
| Definition | tetratricopeptide repeat domain 8 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 12:06:00 | Loss of Bardet-Biedl Syndrome proteins (BBS) proteins Bbs6 and Bbs8 affects ciliated retinal pigment epithelium (RPE). | 30446775 |
| 2019-01-05 12:14:00 | Loss of BBS8 led to changes in the distribution of photoreceptor axonemal proteins and hyper-acetylation of ciliary microtubules. Studies demonstrate the requirement for BBS8 in early development and elaboration of ciliated photoreceptor OS, explaining the need for BBS8 in normal vision. | 29126234 |
| 2015-07-25 11:30:00 | Results show that BBS8 exon 2A is highly photoreceptor specific and the splicing enhancers within the flanking introns are sufficient to drive photoreceptor-specific inclusion of exon 2A and unrelated exons. | 25776555 |
| 2015-03-21 10:35:00 | Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea. | 25605782 |
| 2011-10-01 12:07:00 | Data suggest that loss of BBS8 leads to a dramatic and variable reduction in cilia, which alters the uniformity of responses in populations of olfactory sensory neurons expressing the same receptor, contributing to the observed axon-targeting defects. | 21646512 |
| Type | IDs |
|---|---|
| Synonymous | 0610012F22Rik, AV001447, BBS8 |
| Gene |
UniProtKB-ID:
TTC8_MOUSE
UniprotKB:
Q8VD72
UniParc:
UPI0000021AB6,
UPI0000028A3C
EMBL:
BC017523,
AK081697,
AK002597
Ensembl:
ENSMUSG00000021013
KO:
mmu:76260
|
| Nucleutide sequences |
EMBL-CDS:
AAH17523.1,
BAC38298.1,
BAB22218.1
Ensembl_TRS:
ENSMUST00000079146,
ENSMUST00000085109
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000078148,
ENSMUSP00000082190
RefSeq:
NP_938053.1,
NP_001351307.1,
XP_030102835.1,
NP_083829.1
|
| Others |
UniRef100:
UniRef100_Q8VD72
UniRef90:
UniRef90_Q8VD72
UniRef50:
UniRef50_Q8VD72
UniGene:
Mm.282660
CCDS:
CCDS26102.1,
CCDS26101.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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