| Type | Description |
|---|---|
| Definition | RAS related protein 2a |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 12:15:00 | These results implicate Rap2a in TLR-mediated responses by contributing to balanced NF-kappaB activity status in macrophages. | 30851634 |
| 2018-04-14 10:04:00 | The small GTP-binding protein Rap2a is a common target of both miR-9 and miR-124. miR-9 and miR-124 together, but neither miRNA alone, strongly suppressed Rap2a, thereby promoting neuronal differentiation of neural stem cells and dendritic branching of differentiated neurons. Rap2a also diminished the dendritic complexity of mature neurons by decreasing the levels of pAKT and pGSK3beta. | 27221778 |
| 2010-01-21 00:00:00 | Rap2 has a role in regulation of integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes | 14701796 |
| 2010-01-21 00:00:00 | BCR-induced phosphorylation of Akt on critical activating sites was increased 2- to 3-fold when Rap1 and Rap2 activation was blocked | 12904304 |
| Type | IDs |
|---|---|
| Synonymous | 5830461H18Rik |
| Gene |
UniProtKB-ID:
RAP2A_MOUSE
UniprotKB:
Q80ZJ1
UniParc:
UPI000019627D,
UPI0000025BD8
EMBL:
BC049084,
AK018024,
BC053003,
AK140318,
BC043066
Ensembl:
ENSMUSG00000051615
KO:
mmu:76108
|
| Nucleutide sequences |
EMBL-CDS:
AAH53003.1,
BAB31042.1,
AAH43066.2,
AAH49084.2,
BAE24330.1
Ensembl_TRS:
ENSMUST00000062117
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000056433
RefSeq:
NP_083795.2
|
| Others |
UniRef100:
UniRef100_Q80ZJ1
UniRef90:
UniRef90_P10114
UniRef50:
UniRef50_P10114
UniGene:
Mm.261448
CCDS:
CCDS27341.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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