| Type | Description |
|---|---|
| Definition | dedicator of cytokinesis 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 13:00:00 | Our studies reveal the novel finding that DOCK8 mutant mice, in contrast to the findings in humans, have elevated Th17 cells. Despite this, they do not get exaggerated EAE but appear protected due to a Th17 specific migration defect to the CNS. | 30729501 |
| 2020-04-04 11:16:00 | The DOCK8 is expressed in microglia and regulates microglial activity in disease states. | 31337702 |
| 2017-09-16 11:55:00 | DOCK8 and WASp are in the same signaling pathway that links T-cell receptors (TCRs) to the actin cytoskeleton in TCR-driven actin assembly. | 27599296 |
| 2017-08-12 12:33:00 | LRCH1 as a novel effector to restrain module-induced T cell migration and ameliorate experimental autoimmune encephalomyelitis (EAE). | 28028151 |
| 2017-07-08 12:40:00 | found that DOCK8 associated with LRAP35a, an adaptor molecule that binds to the Cdc42 effector myotonic dystrophy kinase-related Cdc42-binding kinase, and facilitated its activity to phosphorylate myosin II regulatory light chain | 28028174 |
| Type | IDs |
|---|---|
| Synonymous | 1200017A24Rik, 5830472H07Rik, A130095G14Rik, AI461977 |
| Gene |
UniProtKB-ID:
DOCK8_MOUSE
UniprotKB:
Q8C147
UniParc:
UPI00000E95CA,
UPI00004F8E1E
EMBL:
BC030316,
AK038285,
BC029018,
AK028968,
AK004816,
BC043470,
BC055295,
AC132319,
AK131180,
AC139711
Ensembl:
ENSMUSG00000052085
KO:
mmu:76088
|
| Nucleutide sequences |
EMBL-CDS:
BAC29959.1,
AAH55295.1,
AAH29018.2,
BAC26219.2,
AAH30316.2,
AAH43470.1,
BAB23587.1,
BAD21430.1
Ensembl_TRS:
ENSMUST00000025831
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025831
RefSeq:
XP_006527499.1,
XP_006527498.1,
NP_083061.2,
XP_011245699.1
|
| Others |
UniRef100:
UniRef100_Q8C147
UniRef90:
UniRef90_Q8C147
UniRef50:
UniRef50_Q8NF50
UniGene:
Mm.102485
CCDS:
CCDS37943.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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