| Type | Description |
|---|---|
| Definition | polycomb group ring finger 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:28:00 | Polycomb group RING finger protein 5 influences several developmental signaling pathways during the in vitro differentiation of mouse embryonic stem cells. | 32130724 |
| 2018-12-01 11:36:00 | the knockout of Pcgf3, Pcgf5, or both resulted in a 39, 29, and 52% decrease, respectively, in global levels of H2AK119ub1 as compared with wild-type cells, as evidenced by Western blotting. In contrast, no similar change was observed for H3K27me3. | 29054931 |
| 2018-12-01 10:03:00 | Although PCGF5 is not required for embryonic stem cell (ESC) self-renewal, its loss blocks ESC neural differentiation by activating the SMAD2/TGF-beta signaling pathway. | 29765032 |
| 2018-02-10 11:30:00 | Authors conclude that RYBP/YAF2 binding to H2AK119u1 likely underpins the transient interaction of noncanonical PRC1 complexes with Xist RNA domains but does not account for stable interaction of PCGF3/5-PRC1 complexes. | 28596365 |
| 2017-12-30 10:51:00 | hnRNPK recruits PCGF3/5-PRC1 to the Xist RNA B-repeat to establish polycomb-mediated chromosomal silencing. | 29220657 |
| Type | IDs |
|---|---|
| Synonymous | 0610009F02Rik, 1110054A01Rik, 5830406C17Rik, 5830443C21Rik, 9530023M17Rik, AI324127 |
| Gene |
UniProtKB-ID:
PCGF5_MOUSE
UniprotKB:
Q3UK78
UniParc:
UPI00001ECEE3,
UPI0000029DA7
EMBL:
AK146133,
BC145590,
BC139259,
AK002387,
BC139258,
AK017984
Ensembl:
ENSMUSG00000024805
KO:
mmu:76073
|
| Nucleutide sequences |
EMBL-CDS:
AAI39259.1,
BAB22061.1,
BAB31023.1,
BAE26924.1,
AAI39260.1,
AAI45591.1
Ensembl_TRS:
ENSMUST00000062389,
ENSMUST00000071267,
ENSMUST00000225411,
ENSMUST00000225920,
ENSMUST00000224679
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000058730,
ENSMUSP00000153681,
ENSMUSP00000153206,
ENSMUSP00000153464,
ENSMUSP00000071245
RefSeq:
NP_001355621.1,
XP_011245694.1,
NP_083784.1,
NP_001355619.1,
XP_036017615.1,
NP_001355620.1,
NP_001355622.1
|
| Others |
UniRef100:
UniRef100_Q3UK78
UniRef90:
UniRef90_Q3UK78
UniRef50:
UniRef50_Q3UK78
UniGene:
Mm.259180,
Mm.381165,
Mm.488093,
Mm.491199
CCDS:
CCDS89384.1,
CCDS29772.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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