| Type | Description |
|---|---|
| Definition | myeloid zinc finger 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:12:00 | Cigarette smoke modulates binding of the transcription factor MZF1 to the VEGF promoter and regulates VEGF expression in dependence of genetic variation SNP 405. | 32449233 |
| 2020-04-18 10:46:00 | Metallothionein 2A (MT2A)/myeloid zinc-finger 1 (MZF1) may serve as a prognostic marker and a therapeutic target for human gastric cancer. | 30301827 |
| 2019-08-10 12:36:00 | Exogenous expression of the acidic domain of MZF1 repressed the binding of endogenous MZF1 to IGF1R promoter via blocking the interaction with ETS-like gene 1 (ELK1). This blockage not only caused MZF1 protein degradation, but also restrained ELK1 nuclear localization in high-level MZF1-expressing TNBC cells. MZF1, but not ELK1, was necessary for the retention of mesenchymal phenotype by repressing IGF1R promoter activity | 31366500 |
| 2018-11-10 10:41:00 | Mechanistically, FTO enhanced MZF1 expression by reducing m(6)A levels and mRNA stability in MZF1 mRNA transcript, leading to oncogenic functions. | 29842885 |
| 2018-07-07 12:11:00 | MZF1 gene expression was not significantly correlated with PYROXD2 protein expression in the samples of resected tumor tissues, which revealed that the PYROXD2 promoter transcription activity was determined by the aggregated effect of numerous transcription factors. This finding may be helpful in understanding the underlying mechanism which regulates the PYROXD2 expression. | 29048625 |
| Type | IDs |
|---|---|
| Synonymous | MZF-1, MZF1B, ZFP98, ZNF42, ZSCAN6 |
| Gene |
UniProtKB-ID:
MZF1_HUMAN,
A0A024R4T5_HUMAN,
A0A024R4R6_HUMAN
UniprotKB:
P28698,
A0A024R4T5,
A0A024R4R6
UniParc:
UPI0000EE7328,
UPI000002B75D,
UPI0000072863,
UPI000264F472
EMBL:
AF161886,
AF055077,
AC016630,
M58297,
BC053316,
BC007777,
CH471135,
AC016629,
AF055078
Ensembl:
ENSG00000099326
KO:
hsa:7593
|
| Nucleutide sequences |
EMBL-CDS:
AAD55810.1,
AAD55809.1,
AAH07777.1,
AAA59898.1,
AAF80466.1,
AAF80465.1,
EAW72617.1,
AAH53316.1,
EAW72618.1,
EAW72616.1,
EAW72614.1
Gene_ORFName:
hCG_2008714,
hCG_2008714
Ensembl_TRS:
ENST00000599369,
ENST00000594234,
ENST00000215057
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000469378,
ENSP00000469493,
ENSP00000215057
RefSeq:
NP_932172.1,
NP_001253962.1,
NP_003413.2,
XP_011525566.1,
XP_005259261.1,
XP_016882695.1,
XP_024307457.1
|
| Others |
UniRef100:
UniRef100_P28698
UniRef90:
UniRef90_P28698
UniRef50:
UniRef50_P28698
UniGene:
Hs.399810
CCDS:
CCDS59427.1,
CCDS12988.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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