| Type | Description |
|---|---|
| Definition | C-type lectin domain family 4, member g |
| Date | Results | Publications |
|---|---|---|
| 2017-05-20 14:49:00 | This study shows that C-type lectin LSECtin, a member of the DC-SIGN family, is a novel liver regulator for natural killer cells (NK cells). LSECtin could bind to NK cells in a carbohydrate-dependent manner and could regulate the number of hepatic NK cells. | 27184407 |
| 2015-08-08 11:13:00 | Data show that C-type lectin-like domain family 4, member g (Clec4g) suppresses beta-Site amyloid precursor protein cleaving enzyme-1 (BACE1)-mediated amyloid-beta (Abeta) peptides generation. | 25957769 |
| 2014-10-18 12:28:00 | When expressed in B16 melanoma cells, LSECtin promoted tumor growth, whereas its blockade slowed tumor growth in either wild-type or LSECtin-deficient mice. | 24769443 |
| 2013-08-31 11:12:00 | LSECtin-mediated signaling up-regulates the threshold of CD4(+) T cell activation via tuning the expression of Cbl-b. | 22884358 |
| 2013-06-08 12:56:00 | LSECtin may facilitate the reduction of liver inflammation at the cost of delaying virus clearance, an effect that might be hijacked by the virus as an escape mechanism. | 23487419 |
| Type | IDs |
|---|---|
| Synonymous | 4930572L20Rik |
| Gene |
UniProtKB-ID:
CLC4G_MOUSE
UniprotKB:
Q8BNX1
UniParc:
UPI00000EB156
EMBL:
BC025069,
BC087963,
AK079992
Ensembl:
ENSMUSG00000074491
KO:
mmu:75863
|
| Nucleutide sequences |
EMBL-CDS:
AAH25069.1,
AAH87963.1,
BAC37800.1
Ensembl_TRS:
ENSMUST00000062037
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000059574
RefSeq:
NP_083741.1
|
| Others |
UniRef100:
UniRef100_Q8BNX1
UniRef90:
UniRef90_Q8BNX1
UniRef50:
UniRef50_Q8BNX1
UniGene:
Mm.109183
CCDS:
CCDS22072.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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