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75826 Senp2

75826

Senp2

SUMO/sentrin specific peptidase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition SUMO/sentrin specific peptidase 2

研究结论

Date Results Publications
2020-12-26 13:14:00 The requirement of SUMO2/3 for SENP2 mediated extraembryonic and embryonic development. 31625212
2020-09-05 13:55:00 SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation. 31433978
2019-11-30 11:39:00 We demonstrate that the peripheral actions of leptin on fatty acid oxidation are mediated by two different pathways: AMPK causes a rapid increase in fatty acid oxidation, and SENP2 of the pathway causes a slow, prolonged increase in fatty acid oxidation 30902749
2019-09-21 12:26:00 Senp2 could suppress Setdb1 function by de-SUMOylation. In adipocyte Senp2-deficiency mice, accumulation of the SUMOylated Setdb1 suppressed the expression of Pparg and Cebpa genes as well as lipid metabolism-related target genes, which would decrease the ability of lipid storage in adipocytes. 29272473
2018-04-28 11:43:00 Data suggest that SENP2 in hepatic stellate cells is involved in regulation of apoptosis in these cells and in development/reversion of liver fibrosis (here, carbon tetrachloride-induced liver fibrosis). 29535048

名称对应

Type IDs
Synonymous 2310007L05Rik, 4930538C18Rik, AI646780, AW554757, Smt3ip2, SuPr-1, mKIAA1331
Gene
UniProtKB-ID: SENP2_MOUSE
UniprotKB: Q91ZX6
UniParc: UPI00000060D0, UPI000002B35F, UPI0000003FAC
EMBL: BC031652, AK031030, AY188288, AF368904, AK015987
Ensembl: ENSMUSG00000022855
KO: mmu:75826
Nucleutide sequences
EMBL-CDS: AAH31652.1, BAC27222.1, AAO27902.1, BAB30067.1, AAL14437.1
Ensembl_TRS: ENSMUST00000023561
Protein sequencees
Ensembl_PRO: ENSMUSP00000023561
RefSeq: XP_030105183.1, NP_001344353.1, XP_006522751.1, XP_006522752.1, NP_083733.1, XP_030105184.1
Others
UniRef100: UniRef100_Q91ZX6
UniRef90: UniRef90_Q91ZX6
UniRef50: UniRef50_Q91ZX6
UniGene: Mm.297431
CCDS: CCDS28065.1

全选

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研究热度

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