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75770 Brsk2

75770

Brsk2

BR serine/threonine kinase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition BR serine/threonine kinase 2

研究结论

Date Results Publications
2020-10-10 12:57:00 Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex. 30307479
2019-10-12 13:00:00 SAD-A is activated by the incretin hormone GLP-1 in pancreatic beta-cell. SAD-A promotes the phosphorylation of Bad S155. 30573363
2019-03-02 10:56:00 Glucose and incretin stimulate insulin secretion through the phosphorylation of GDIalpha at Ser174 by SAD-A, which leads to the activation of Rho GTPases, culminating in insulin exocytosis. 29873699
2016-05-21 12:11:00 Taken together, these data suggest a model for synergistic autoinhibition and membrane activation of SAD kinases. 26626945
2014-06-07 12:53:00 SAD-A and AMPK kinases are regulators of mTORC1 signaling in the pancreatic beta-cells. 24047693

名称对应

Type IDs
Synonymous 4833424K13Rik, SAD-A, SADA
Gene
UniProtKB-ID: BRSK2_MOUSE, G3FEZ6_MOUSE
UniprotKB: Q69Z98, G3FEZ6
UniParc: UPI00004016CC, UPI00001C3F55, UPI0000E6A7B4, UPI00005640CC, UPI00001F5977
EMBL: AL772165, AY533673, AY533672, AL603836, BC056498, AY533674, JF707772, AK173268, AY660739
Ensembl: ENSMUSG00000053046
KO: mmu:75770
Nucleutide sequences
EMBL-CDS: AAT08449.1, AAT08448.1, AAT74618.1, AAT08447.1, BAD32546.1, AAH56498.1, AEO80313.1
Ensembl_TRS: ENSMUST00000018971, ENSMUST00000075528, ENSMUST00000174499, ENSMUST00000105989, ENSMUST00000078200
Protein sequencees
Ensembl_PRO: ENSMUSP00000077330, ENSMUSP00000101610, ENSMUSP00000134201, ENSMUSP00000074969, ENSMUSP00000018971
RefSeq: NP_083702.1, NP_001009930.1, NP_001263692.1, NP_001009929.1
Others
UniRef100: UniRef100_G3FEZ6, UniRef100_Q69Z98
UniRef90: UniRef90_Q69Z98, UniRef90_G3FEZ6
UniRef50: UniRef50_Q69Z98, UniRef50_A0A2K5YL51
UniGene: Mm.274868, Mm.482784
CCDS: CCDS22022.1, CCDS22023.1, CCDS22021.1

全选

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