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75735 Pank1

75735

Pank1

pantothenate kinase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition pantothenate kinase 1

研究结论

Date Results Publications
2016-10-01 10:59:00 Pank1 genetic deficiency can be corrected using phosphopantothenate diet replacement therapy. 26549575
2015-01-31 11:37:00 The results indicate that Pank1 deficiency drives a whole-body metabolic adaptation that improves aspects of the diabetic phenotype and uncouples hyperglycaemia and hyperinsulinaemia from obesity in leptin-deficient mice. 24781151
2013-08-31 12:36:00 p53 plays an important role in regulating energy homeostasis through transcriptional control of PANK1. 23343762
2013-03-23 11:02:00 The data indicate that PanK1 and PanK2 can compensate for each other to supply tissue CoA. 22815849
2010-09-06 12:21:00 data illustrate the importance of PanK1 and elevated liver CoA levels during fasting to support the metabolic transition from glucose utilization and fatty acid synthesis to gluconeogenesis and fatty acid oxidation 20559429

名称对应

Type IDs
Synonymous Pank, Pank1b
Gene
UniProtKB-ID: PANK1_MOUSE, Q543J7_MOUSE
UniprotKB: Q8K4K6, Q543J7
UniParc: UPI0000028C99, UPI00000040A8
EMBL: AF347700, AF200357, BC023496, AK017345, AK050222
Ensembl: ENSMUSG00000033610
KO: mmu:75735
Nucleutide sequences
EMBL-CDS: AAH23496.1, AAM77216.1, BAB30700.1, AAF23952.1, BAC34132.1
Ensembl_TRS: ENSMUST00000112460, ENSMUST00000036584
Protein sequencees
Ensembl_PRO: ENSMUSP00000043562, ENSMUSP00000108079
RefSeq: NP_076281.1, XP_006527490.1, NP_001107811.1, XP_030106986.1
Others
UniRef100: UniRef100_Q8K4K6, UniRef100_Q543J7
UniRef90: UniRef90_Q8K4K6, UniRef90_D3ZWD3
UniRef50: UniRef50_Q8R2W9, UniRef50_Q9BZ23
UniGene: Mm.24742
CCDS: CCDS50424.1, CCDS37966.1

全选

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研究热度

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