| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 4B |
| Date | Results | Publications |
|---|---|---|
| 2016-06-28 11:21:00 | PKR inhibition reduced the expression of eIF4B and C/EBPbeta in an eIF2alpha-independent manner | 26646662 |
| 2013-02-16 12:06:00 | Maintenance of eIF4E interaction with eIF4G was not by itself sufficient to sustain global rates of protein synthesis in the absence of mTORC1 signaling to p70S6K1; phosphorylation of both eIF4B and PDCD4 was additionally required. | 23105104 |
| 2011-12-24 10:04:00 | C-loops bind to eIF4B and prevent the factor's interaction with 18S rRNA of the small ribosomal subunit. | 21930783 |
| 2010-01-21 00:00:00 | These data provide novel insights into complex multikinase regulation of eIF4B phosphorylation and reveal an important mechanism by which PKB can regulate translation, potentially critical for the transforming capacity of this AGC kinase family member. | 18836482 |
| 2010-01-21 00:00:00 | Phosphorylation of eIF4B on Ser422 by p90 ribosomal protein S6 kinase (RSK) and S6K is physiologically significant, as it increases the interaction of eIF4B with the eukaryotic translation initiation factor 3. | 16763566 |
| Type | IDs |
|---|---|
| Synonymous | 2310046H11Rik, AL024095, C85189, Eif4a2 |
| Gene |
UniProtKB-ID:
IF4B_MOUSE
UniprotKB:
Q8BGD9
UniParc:
UPI00000EBA1E
EMBL:
AK077423,
AK045250,
AK170354
Ensembl:
ENSMUSG00000058655
KO:
mmu:75705
|
| Nucleutide sequences |
EMBL-CDS:
BAC32280.1,
BAC36793.1,
BAE41740.1
Ensembl_TRS:
ENSMUST00000169681
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000127774
RefSeq:
NP_663600.2
|
| Others |
UniRef100:
UniRef100_Q8BGD9
UniRef90:
UniRef90_P23588-2
UniRef50:
UniRef50_P23588-2
UniGene:
Mm.290022,
Mm.391795
CCDS:
CCDS49737.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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