| Type | Description |
|---|---|
| Definition | nonhomologous end-joining factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:09:00 | An in vivo study of the impact of deficiency in the DNA repair proteins PAXX and XLF on development and maturation of the hemolymphoid system. | 31915249 |
| 2020-09-05 13:52:00 | Cernunnos/Xlf Deficiency Results in Suboptimal V(D)J Recombination and Impaired Lymphoid Development in Mice. | 30923523 |
| 2020-05-16 12:14:00 | We propose that XLF and H2AX function in series to prevent replication stress induced by the MRE11-dependent resection of regressed arms at reversed replication forks. | 31123184 |
| 2019-08-24 12:50:00 | This damaging phenotype highlights the functional nexus between Xlf and Xrcc4, which is critical for the completion of NHEJ-dependent mechanisms during mouse development. | 29077092 |
| 2019-07-20 12:17:00 | Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53 | 30579708 |
| Type | IDs |
|---|---|
| Synonymous | 1700029B21Rik, XLF, cernunnos |
| Gene |
UniProtKB-ID:
NHEJ1_MOUSE
UniprotKB:
Q3KNJ2
UniParc:
UPI00006C21C8,
UPI00005C3FEF
EMBL:
BC132361,
BC107253,
BC107252,
BC132359,
AK006481,
BC006063
KO:
mmu:75570
|
| Nucleutide sequences |
EMBL-CDS:
AAI07254.1,
AAI32362.1,
AAI07253.1,
AAH06063.1,
BAB24611.1,
AAI32360.1
|
| Protein sequencees |
RefSeq:
NP_083618.3
|
| Others |
UniRef100:
UniRef100_Q3KNJ2
UniRef90:
UniRef90_Q3KNJ2
UniRef50:
UniRef50_Q3KNJ2
UniGene:
Mm.442409
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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