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75547 Akap13

75547

Akap13

A kinase (PRKA) anchor protein 13

protein-coding

Mus musculus

基因描述

Type Description
Definition A kinase (PRKA) anchor protein 13

研究结论

Date Results Publications
2019-06-08 10:51:00 Akap13 haploinsufficiency led to sex-dependent, compulsive-like behavioral changes in a murine model. Interestingly, Akap13 haploinsufficiency also led to a sex-dependent increase in body weight. 29653158
2016-06-28 10:14:00 These findings suggest that Akap13 haploinsufficient mice have a deficiency in early osteogenesis with a corresponding reduction in osteoblast number, but no impairment of mature osteoblast activity. 25892096
2016-04-23 10:36:00 Our results show that AKAP13-PKD1 signaling is critical for transcriptional regulation of key contractile, cell death, and metabolic pathways during the development of compensatory hypertrophy in vivo. 26192751
2014-08-23 11:54:00 The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy. 24161911
2013-12-14 10:39:00 AKAP13 Rho-GEF and PKD-binding domains are important for normal cardiac contractility. 23658642

名称对应

Type IDs
Synonymous 1700026G02Rik, 5730522G15Rik, 5830460E08Rik, AKAP-13, AKAP-Lbc, BRX, Ht31, LBC, PROTO-LB, PROTO-LBC
Gene
UniProtKB-ID: AKP13_MOUSE, A0A140LJJ5_MOUSE
UniprotKB: E9Q394, A0A140LJJ5
UniParc: UPI0000605887, UPI0000F4FEF0, UPI0001754DCE
EMBL: AK149507, AC113019, AC158749
Ensembl: ENSMUSG00000066406
KO: mmu:75547
Nucleutide sequences
EMBL-CDS: BAE28926.1
Ensembl_TRS: ENSMUST00000166315, ENSMUST00000207750
Protein sequencees
Ensembl_PRO: ENSMUSP00000129784, ENSMUSP00000147237
RefSeq: XP_006541318.1, XP_036009423.1, XP_036009416.1, XP_006541316.1, XP_036009422.1, XP_030098925.1, XP_036009425.1, XP_036009419.1, XP_006541321.1, XP_036009424.1, XP_006541319.1, XP_036009414.1, XP_036009421.1, XP_036009417.1, NP_083608.1, XP_036009420.1, XP_006541317.1, XP_030098922.1, XP_036009413.1, XP_036009418.1, XP_036009426.1, XP_036009415.1, XP_006541323.1, XP_006541322.1
Others
UniRef100: UniRef100_E9Q394, UniRef100_A0A140LJJ5
UniRef90: UniRef90_E9Q394
UniRef50: UniRef50_Q12802
UniGene: Mm.216107
CCDS: CCDS52276.1

全选

研究热度
发表文献
热点单位
排名 科研单位 文献
1

Gladstone Institute of Cardiovascular Disease

3
2

Telethon Institute of Genetics and Medicine

2
3

Institute of Developmental Genetics

2
4

College of Medicine

2
5

National Institutes of Health

2
热点人员
排名 研究人员 文献
1

P Carninci

7
2

Y Hayashizaki

6
3

K Shibata

5
4

M Itoh

5
5

H Konno

5
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