| Type | Description |
|---|---|
| Definition | 5-oxoprolinase (ATP-hydrolysing) |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 11:52:00 | Oplah full body knock-out mice had higher 5-oxoproline levels coupled to increased oxidative stress, myocardial fibrosis and elevated filling pressures reminiscent of heart failure with preserved ejection fraction. | 30032247 |
| 2018-06-23 11:44:00 | OPLAH depletion occurred as a result of cardiac injury, leading to elevated 5-oxoproline and oxidative stress, whereas OPLAH overexpression improved cardiac function after ischemic injury. | 29118264 |
| 2010-08-09 12:15:00 | the cause of cellular ATP depletion in nephrotic cystinosis may be the futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase | 20413906 |
| Type | IDs |
|---|---|
| Synonymous | 1700010G02Rik, 5-OPase |
| Gene |
UniProtKB-ID:
OPLA_MOUSE
UniprotKB:
Q8K010
UniParc:
UPI0000027F9A
EMBL:
BC025120,
BC034522
Ensembl:
ENSMUSG00000022562
KO:
mmu:75475
|
| Nucleutide sequences |
EMBL-CDS:
AAH34522.1,
AAH25120.1
Ensembl_TRS:
ENSMUST00000023222,
ENSMUST00000171340
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129100,
ENSMUSP00000023222
RefSeq:
NP_694762.1,
XP_006521570.1,
XP_006521572.1,
XP_006521571.1,
XP_030104667.1,
XP_030104666.1
|
| Others |
UniRef100:
UniRef100_Q8K010
UniRef90:
UniRef90_O14841
UniRef50:
UniRef50_O14841
UniGene:
Mm.322738
CCDS:
CCDS27565.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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