| Type | Description |
|---|---|
| Definition | Zic family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:16:00 | ZIC2 is downregulated and represses tumor growth via the regulation of in breast cancer. | 32064600 |
| 2021-01-26 11:12:00 | ZIC2 regulates laterality of cardiovascular system. A subset of holoprosencephaly cases with ZIC2 mutation also exhibit heterotaxy. Mouse mutant shows right isomerism indicating lack of left-sided Nodal signalling in the embryo. Mechanistic studies in vitro indicate that ZIC2 is required for Nodal expression at the embryonic node and binds to the Nodal HBE enhancer in epiblast. | 29992973 |
| 2020-12-12 13:21:00 | MicroRNA-129-5p suppresses nasopharyngeal carcinoma lymphangiogenesis and lymph node metastasis by targeting ZIC2. | 31884576 |
| 2020-08-01 14:37:00 | Results identified loss of ZIC2 expression following DNA hypomethylation as a promising prognostic biomarker for prostate cancer. | 31640781 |
| 2019-06-01 12:28:00 | MiR12715p inhibited the progression of AML by targeting ZIC2. | 30483794 |
| Type | IDs |
|---|---|
| Synonymous | HPE5 |
| Gene |
UniProtKB-ID:
ZIC2_HUMAN,
A0A024RDY6_HUMAN
UniprotKB:
O95409,
A0A024RDY6
UniParc:
UPI000013C3DC
EMBL:
AL355338,
CH471085,
AF104902,
AF193855
Ensembl:
ENSG00000043355
KO:
hsa:7546
|
| Nucleutide sequences |
EMBL-CDS:
AAC96325.1,
AAG28409.1,
EAX09030.1,
EAX09031.1
Gene_ORFName:
hCG_24577
Ensembl_TRS:
ENST00000376335
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365514
RefSeq:
NP_009060.2
|
| Others |
UniRef100:
UniRef100_O95409
UniRef90:
UniRef90_O95409
UniRef50:
UniRef50_Q62520
UniGene:
Hs.653700
CCDS:
CCDS9495.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员