| Type | Description |
|---|---|
| Definition | Zic family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:56:00 | Zic1 suppresses gastric cancer metastasis by regulating Wnt/beta-catenin signaling and epithelial-mesenchymal transition. | 31909528 |
| 2020-09-12 15:59:00 | A single factor induces neuronal differentiation to suppress glioma cell growth. | 30264483 |
| 2019-02-23 13:02:00 | this severe brain malformation indicates that premature closure of sutures can be independent of the abnormal brain development in subjects with pathogenic variants in ZIC1. | 30391508 |
| 2018-12-01 11:04:00 | Study demonstrate that ZIC1 plays a tumor suppressive role in breast cancer, by targeting surviving, significantly downregulating its expression. | 29956756 |
| 2018-07-14 10:28:00 | Two proposed mechanisms for Zic-mediated cerebellar developmental control have been documented: regulation of neuronal progenitor proliferation-differentiation and the patterning of the cerebellar primordium. Clinical studies have also revealed that ZIC1 gain of function mutations contribute to coronal craniosynostosis, a rare skull malformation. | 29442326 |
| Type | IDs |
|---|---|
| Synonymous | CRS6, ZIC, ZNF201 |
| Gene |
UniProtKB-ID:
ZIC1_HUMAN
UniprotKB:
Q15915
UniParc:
UPI000013DD09
EMBL:
BC104848,
BC104850,
CH471052,
D76435
Ensembl:
ENSG00000152977
KO:
hsa:7545
|
| Nucleutide sequences |
EMBL-CDS:
BAA11179.1,
AAI04851.1,
EAW78915.1,
AAI04849.1
Ensembl_TRS:
ENST00000282928
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000282928
RefSeq:
NP_003403.2
|
| Others |
UniRef100:
UniRef100_Q15915
UniRef90:
UniRef90_Q15915
UniRef50:
UniRef50_Q15915
UniGene:
Hs.598590,
Hs.647962
CCDS:
CCDS3136.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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