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75404 Arhgap36

75404

Arhgap36

Rho GTPase activating protein 36

protein-coding

Mus musculus

基因描述

Type Description
Definition Rho GTPase activating protein 36

研究结论

Date Results Publications
2020-02-29 10:42:00 AKT stimulates the Shh activity to induce lateral motor columnar motor neurons through the stabilization of ARHGAP36 proteins. 31305241
2014-11-08 12:09:00 a new mechanism of Gli transcription factor activation and implicate ARHGAP36 dysregulation in the onset and/or progression of GLI-dependent cancers. 25024229
2014-09-19 16:46:00 Arhgap36 acts in a Smoothened-independent manner to promote the activation of full-length Gli proteins and induces the accumulation of Gli proteins in the primary cilium. Its ability to induce Gli-dependent transcription requires kinesin family member 3a and intraflagellar transport protein 88, proteins that are essential for ciliogenesis. Arhgap36 functionally and biochemically interacts with Suppressor of Fused. 25024229

名称对应

Type IDs
Synonymous 1100001E04Rik, rho-gap
Gene
UniProtKB-ID: RHG36_MOUSE
UniprotKB: B1AUC7
UniParc: UPI000150B038, UPI00001E4025, UPI00001F8232
EMBL: BC090672, AL670305, AB073967, BC145645
Ensembl: ENSMUSG00000036198
KO: mmu:75404
Nucleutide sequences
EMBL-CDS: AAI45646.1, BAF81999.1, CAM17962.1, CAM17961.1, CAM17960.1, AAH90672.1
Ensembl_TRS: ENSMUST00000114904
Protein sequencees
Ensembl_PRO: ENSMUSP00000110554
RefSeq: NP_001343323.1, NP_001074592.1, XP_017174121.1, XP_006541617.1, XP_017174122.1, XP_006541618.1, XP_030107375.1
Others
UniRef100: UniRef100_B1AUC7
UniRef90: UniRef90_B1AUC7
UniRef50: UniRef50_Q6ZRI8
UniGene: Mm.44305, Mm.491395
CCDS: CCDS40963.1

全选

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