| Type | Description |
|---|---|
| Definition | zeta chain of T cell receptor associated protein kinase 70 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:22:00 | A micropatterning platform for quantifying interaction kinetics between the T cell receptor and an intracellular binding protein. | 30824760 |
| 2020-08-01 15:15:00 | basal ZAP70 activation in resting T cell lines reduced the threshold ("primed") TCR-stimulated activation of the classical p38 pathway | 31337738 |
| 2020-07-04 10:59:00 | These findings demonstrate that plays an important role in a positive feedback regulatory loop that modulates TCR-proximal signaling and, moreover, provide a mechanistic explanation for earlier reports that documented an important role for duanyu1531theta; in T cell Ca(2+) signaling. This interaction could potentially serve as a promising and highly selective immunosuppressive drug target in autoimmu... | 30992398 |
| 2020-05-30 12:59:00 | Measuring the T-cell down-regulation of TCR-zeta, ZAP-70 and CD28 in arthritis patients: An old tool for new biomarkers. | 31400229 |
| 2019-10-26 12:30:00 | Study found that CCR7 is recruited to the immunological synapse and acts as co-stimulatory molecule in human T cells. CCR7 associates with the zeta chain of the TCR and recruits and activates the tyrosine kinase ZAP70 upon chemokine triggering. | 30692994 |
| Type | IDs |
|---|---|
| Synonymous | ADMIO2, IMD48, SRK, STCD, STD, TZK, ZAP-70 |
| Gene |
UniProtKB-ID:
ZAP70_HUMAN
UniprotKB:
P43403
UniParc:
UPI000011C8BA,
UPI000013C370,
UPI00000743CC
EMBL:
BC053878,
AB083211,
L05148,
AC016699,
BC039039
Ensembl:
ENSG00000115085
KO:
hsa:7535
|
| Nucleutide sequences |
EMBL-CDS:
AAX93187.1,
AAH53878.1,
BAC43747.1,
AAH39039.1
Ensembl_TRS:
ENST00000264972,
ENST00000451498
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000264972,
ENSP00000400475
RefSeq:
NP_997402.1,
NP_001070.2,
XP_016860357.1,
XP_016860359.1,
XP_016860358.1,
XP_016860356.1,
NP_001365523.1
|
| Others |
UniRef100:
UniRef100_P43403
UniRef90:
UniRef90_P43403
UniRef50:
UniRef50_P43403
UniGene:
Hs.234569
CCDS:
CCDS33254.1,
CCDS33255.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员