| Type | Description |
|---|---|
| Definition | YES proto-oncogene 1, Src family tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:37:00 | Overexpression of YES1 is associated with favorable prognosis and increased platinum-sensitivity in patients with epithelial ovarian cancer. | 31970720 |
| 2021-01-09 13:30:00 | MiR-133 Targets YES1 and Inhibits the Growth of Triple-Negative Breast | 32462982 |
| 2020-11-21 13:13:00 | Genome-Wide Analysis Identifies Two Susceptibility Loci for Positive Thyroid Peroxidase and Thyroglobulin Antibodies. | 31794020 |
| 2020-03-21 11:03:00 | YES1 is essential for NSCLC carcinogenesis. YES1 overexpression induced metastatic spread in preclinical in vivo models. YES1 genetic depletion by CRISPR/Cas9 technology significantly reduced tumor growth and metastasis. | 31166114 |
| 2020-03-21 10:37:00 | YES1 plays an important role in the emergence of resistance to HER2-targeted drugs. | 31856375 |
| Type | IDs |
|---|---|
| Synonymous | HsT441, P61-YES, Yes, c-yes |
| Gene |
UniProtKB-ID:
YES_HUMAN
UniprotKB:
P07947
UniParc:
UPI0000062316
EMBL:
AP001178,
CH471113,
M15990,
BC048960
Ensembl:
ENSG00000176105
KO:
hsa:7525
|
| Nucleutide sequences |
EMBL-CDS:
AAA35735.1,
EAX01709.1,
AAH48960.1,
EAX01710.1
Ensembl_TRS:
ENST00000314574,
ENST00000584307
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000462468,
ENSP00000324740
RefSeq:
XP_016881449.1,
XP_024307011.1,
XP_024307015.1,
XP_024307014.1,
XP_024307012.1,
XP_024307013.1,
NP_005424.1,
XP_005258196.1
|
| Others |
UniRef100:
UniRef100_P07947
UniRef90:
UniRef90_P07947
UniRef50:
UniRef50_P07947
UniGene:
Hs.194148
CCDS:
CCDS11824.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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