| Type | Description |
|---|---|
| Definition | meiosis specific with OB domains |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:53:00 | The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination. | 33166385 |
| 2020-11-23 11:35:00 | Two mutations (N64I and S67 deletion) in MEIOB cause self-aggregation of MEIOB and sharply reduced protein half-life. In addition to a role in early meiotic recombination, plays a role in late meiotic recombination, i.e., in crossover formation, in a dosage-dependent manner. | 33166385 |
| 2020-11-23 11:34:00 | Aspartic acid 383 (D383) in MEIOB is essential for meiosis in mice. Isocotoin, a small molecule, inhibits the interaction and promotes their degradation in HEK293 cells in a dose-dependent manner. | 32463099 |
| 2018-06-16 11:55:00 | We find that MEIOB and form an obligate complex and contain defined interaction domains | 28453612 |
| 2017-12-14 11:27:00 | MEIOB and form an obligate complex and contain defined interaction domains. A single residue D383 in MEIOB is indispensable for the interaction. The complex interacts with the RPA heterotrimeric complex in a collaborative manner. | 28453612 |
| Type | IDs |
|---|---|
| Synonymous | 4930528F23Rik, MLZ-675 |
| Gene |
UniProtKB-ID:
MEIOB_MOUSE
UniprotKB:
Q9D513
UniParc:
UPI0001B09237
EMBL:
AK015924,
BC119087,
BC119085,
AC166102
Ensembl:
ENSMUSG00000024155
KO:
mmu:75178
|
| Nucleutide sequences |
EMBL-CDS:
AAI19086.1,
AAI19088.1,
BAB30034.1
Ensembl_TRS:
ENSMUST00000024972
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024972
RefSeq:
XP_006525110.1,
XP_006525115.1,
XP_006525108.1,
NP_083473.1,
XP_017173191.1,
XP_006525111.1
|
| Others |
UniRef100:
UniRef100_Q9D513
UniRef90:
UniRef90_Q9D513
UniRef50:
UniRef50_Q9D513
UniGene:
Mm.52592
CCDS:
CCDS50020.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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