| Type | Description |
|---|---|
| Definition | Wnt family member 10B |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:03:00 | No genotype-phenotype correlation is delineated but heterozygous individuals might have mild features of split hand/foot malformation, suggesting a dose-effect of the WNT10B loss-of-function | 31050392 |
| 2020-02-22 11:59:00 | results suggest a dual role for Wnt family member 10B protein (WNT10B) in normal development and in prostate cancer progression with opposing functions depending on disease stage | 31433503 |
| 2020-02-15 10:18:00 | Study shows for the first time significant ultraviolet B induced upregulation of WNT7B, WNT10B and TCF7L2 in patients with psoriasis and suggests a potential role of these genes in psoriasis pathogenesis. | 31089877 |
| 2019-12-14 12:26:00 | Authors define WNT10B-dependent biomarkers for beta-CATENIN/HMGA2/EZH2 signaling predictive of reduced relapse-free survival. | 30563890 |
| 2019-09-28 11:49:00 | In 7 families afflicted with dental anomalies we detected 4 heterozygous missense variants in WNT10B. We performed whole exome sequencing in the patients who had WNT10B mutations and found no mutations in other known hypodontia-associated genes..They also show that WNT10B variants are associated not only with oligodontia and isolated tooth agenesis, but also with microdontia, short tooth roots, dental pulp stones | 29364501 |
| Type | IDs |
|---|---|
| Synonymous | SHFM6, STHAG8, WNT-12 |
| Gene |
UniProtKB-ID:
WN10B_HUMAN
UniprotKB:
O00744
UniParc:
UPI0000138F21,
UPI000050ED7F
EMBL:
X97057,
BC096353,
AK312906,
U81787,
AB070724,
BC096355,
BC096356,
AF028700,
AC073610,
CH471111,
BC096354
Ensembl:
ENSG00000169884
KO:
hsa:7480
|
| Nucleutide sequences |
EMBL-CDS:
EAW58028.1,
BAG35752.1,
BAB72181.1,
AAC39549.1,
CAA65769.1,
AAH96355.1,
AAB51685.1,
AAH96356.1,
AAH96354.1,
AAH96353.1
Ensembl_TRS:
ENST00000407467,
ENST00000301061
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000301061,
ENSP00000384691
RefSeq:
XP_011537024.1,
XP_011537026.1,
NP_003385.2,
XP_016875408.1,
XP_024304947.1
|
| Others |
UniRef100:
UniRef100_O00744
UniRef90:
UniRef90_P48614
UniRef50:
UniRef50_P48614
UniGene:
Hs.91985
CCDS:
CCDS8775.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员