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74777 Selenon

74777

Selenon

selenoprotein N

protein-coding

Mus musculus

基因描述

Type Description
Definition selenoprotein N

研究结论

Date Results Publications
2019-03-23 10:56:00 These findings suggest that SELENON is part of an ER stress-dependent antioxidant response and that the CHOP/ERO1 branch of the ER stress response is a novel pathogenic mechanism underlying SELENON-related myopathies. 30391828
2018-09-15 10:03:00 Se played an important role in regulating the process of contraction in uterine smooth muscle with SelN. 28836095
2016-01-16 10:07:00 SEPN1 enhances SERCA2 activity by reducing luminal cysteines that are hyperoxidized by ERO1-generated peroxides. 25452428
2013-06-22 12:05:00 SepN deficiency leads to abnormal lung development characterized by enlarged alveoli, which is associated with decreased tissue elastance and increased quasi-static compliance of Sepn1(-/-) lungs. 23325319
2012-02-18 10:35:00 Data show that Sepn1(-/-) mice developed an obvious phenotype, characterized by limited motility and body rigidity during the swimming session. 21858002

名称对应

Type IDs
Synonymous 1110019I12Rik, AI414492, SelN, Sepn1
Gene
UniProtKB-ID: SELN_MOUSE
UniprotKB: D3Z2R5
UniParc: UPI000059E179
EMBL: AL669982
Ensembl: ENSMUSG00000050989
KO: mmu:74777
Nucleutide sequences
Ensembl_TRS: ENSMUST00000060435
Protein sequencees
Ensembl_PRO: ENSMUSP00000060026
RefSeq: NP_083376.2
Others
UniRef100: UniRef100_D3Z2R5
UniRef90: UniRef90_D3Z2R5
UniRef50: UniRef50_Q9NZV5
UniGene: Mm.29773
CCDS: CCDS38917.1

全选

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研究热度

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