| Type | Description |
|---|---|
| Definition | Wnt family member 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 11:52:00 | Secreted Wnt6 binds to FZD4 to activate the canonical Wnt6 signaling pathway, which is upstream of ROCK1 and 14-3-3sigma, and that this is the cell signaling pathway underlying diabetes-associated centrosome amplification. | 31618077 |
| 2019-09-07 12:42:00 | The authors show that WNT6 is significantly overexpressed in glioblastoma, as compared to lower-grade gliomas and normal brain, at mRNA and protein levels. Functionally, WNT6 increases typical oncogenic activities in glioblastoma cells, including viability, proliferation, glioma stem cell capacity, invasion, migration, and resistance to temozolomide chemotherapy. | 30279739 |
| 2019-02-02 11:25:00 | Study results indicated that PLAGL2 was overexpressed in colorectal cancer (CRC) as a protooncogene and that it could active the Wnt/betacatenin pathway as a transcription factor by binding with the promoter region of Wnt6. | 30535429 |
| 2018-12-22 12:01:00 | WNT6 may be a diagnostic and prognostic marker in osteosarcoma | 30431574 |
| 2016-12-17 10:58:00 | our results support the concept that WNT6 may play a role in tumor progression | 26617869 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
WNT6_HUMAN,
Q8N2E5_HUMAN
UniprotKB:
Q9Y6F9,
Q8N2E5
UniParc:
UPI000003B0EC,
UPI0000051047
EMBL:
AK075522,
AB059570,
BC004329,
BT007456,
AF315943,
AY009401,
AF079522
Ensembl:
ENSG00000115596
KO:
hsa:7475
|
| Nucleutide sequences |
EMBL-CDS:
AAG45154.1,
AAG38661.1,
BAB55603.1,
AAP36124.1,
AAD41674.1,
AAH04329.1,
BAC11668.1
Ensembl_TRS:
ENST00000233948
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000233948
RefSeq:
NP_006513.1
|
| Others |
UniRef100:
UniRef100_Q9Y6F9,
UniRef100_Q8N2E5
UniRef90:
UniRef90_P22727,
UniRef90_Q9Y6F9
UniRef50:
UniRef50_P22727
UniGene:
Hs.29764
CCDS:
CCDS2425.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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