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74732 Stx11

74732

Stx11

syntaxin 11

protein-coding

Mus musculus

基因描述

Type Description
Definition syntaxin 11

研究结论

Date Results Publications
2019-09-14 11:17:00 Findings suggest that stx11 regulates the stimulus-dependent transport of TLR4 to the plasma membrane by cooperating with SNAP-23 in macrophages. Our results clarify the regulatory mechanisms underlying intracellular transport of TLR4 and have implications for microbial pathogenesis and immune responses. 30811271
2013-04-13 11:33:00 required for NK and CD8+ T cell cytotoxicity and neutrophil degranulation 23042080
2013-03-23 11:57:00 Blockade of inhibitory receptors on T cells in Stx11-deficient mice converted nonfatal disease course into fatal HLH, identifying T-cell exhaustion as an important factor for determination of disease severity in hemophagocytic lymphohistiocytosis. 23190531
2013-03-23 11:57:00 Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11. 23160464
2011-08-27 10:36:00 Results suggest that by regulating the availability of Vti1b, Stx11 regulates trafficking steps between late endosomes, lysosomes and the cell surface in macrophages. 21388490

名称对应

Type IDs
Synonymous 5830405C08Rik
Gene
UniProtKB-ID: STX11_MOUSE, Q3U5V8_MOUSE
UniprotKB: Q9D3G5, Q3U5V8
UniParc: UPI0000025722, UPI0000029DBB
EMBL: AK153408, AL691505, AK017897
Ensembl: ENSMUSG00000039232
KO: mmu:74732
Nucleutide sequences
EMBL-CDS: BAB30994.1, BAE31968.1
Ensembl_TRS: ENSMUST00000042861, ENSMUST00000163425
Protein sequencees
Ensembl_PRO: ENSMUSP00000132758, ENSMUSP00000046243
RefSeq: XP_006512949.1, XP_006512951.1, NP_001157063.1, XP_006512950.1, NP_083351.1, NP_001157062.1
Others
UniRef100: UniRef100_Q9D3G5, UniRef100_Q3U5V8
UniRef90: UniRef90_Q9D3G5
UniRef50: UniRef50_Q9D3G5
UniGene: Mm.248648
CCDS: CCDS48500.1

全选

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