Type | Description |
---|---|
Definition | syntaxin 11 |
Date | Results | Publications |
---|---|---|
2019-09-14 11:17:00 | Findings suggest that stx11 regulates the stimulus-dependent transport of TLR4 to the plasma membrane by cooperating with SNAP-23 in macrophages. Our results clarify the regulatory mechanisms underlying intracellular transport of TLR4 and have implications for microbial pathogenesis and immune responses. | 30811271 |
2013-04-13 11:33:00 | required for NK and CD8+ T cell cytotoxicity and neutrophil degranulation | 23042080 |
2013-03-23 11:57:00 | Blockade of inhibitory receptors on T cells in Stx11-deficient mice converted nonfatal disease course into fatal HLH, identifying T-cell exhaustion as an important factor for determination of disease severity in hemophagocytic lymphohistiocytosis. | 23190531 |
2013-03-23 11:57:00 | Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11. | 23160464 |
2011-08-27 10:36:00 | Results suggest that by regulating the availability of Vti1b, Stx11 regulates trafficking steps between late endosomes, lysosomes and the cell surface in macrophages. | 21388490 |
Type | IDs |
---|---|
Synonymous | 5830405C08Rik |
Gene |
UniProtKB-ID:
STX11_MOUSE,
Q3U5V8_MOUSE
UniprotKB:
Q9D3G5,
Q3U5V8
UniParc:
UPI0000025722,
UPI0000029DBB
EMBL:
AK153408,
AL691505,
AK017897
Ensembl:
ENSMUSG00000039232
KO:
mmu:74732
|
Nucleutide sequences |
EMBL-CDS:
BAB30994.1,
BAE31968.1
Ensembl_TRS:
ENSMUST00000042861,
ENSMUST00000163425
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000132758,
ENSMUSP00000046243
RefSeq:
XP_006512949.1,
XP_006512951.1,
NP_001157063.1,
XP_006512950.1,
NP_083351.1,
NP_001157062.1
|
Others |
UniRef100:
UniRef100_Q9D3G5,
UniRef100_Q3U5V8
UniRef90:
UniRef90_Q9D3G5
UniRef50:
UniRef50_Q9D3G5
UniGene:
Mm.248648
CCDS:
CCDS48500.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员