Type | Description |
---|---|
Definition | negative elongation factor complex member A |
Date | Results | Publications |
---|---|---|
2021-03-20 13:35:00 | Stress-induced nuclear condensation of NELF drives transcriptional downregulation. | 33548202 |
2021-02-06 13:49:00 | The noncoding function of NELFA mRNA promotes the development of oesophageal squamous cell carcinoma by regulating the Rad17-RFC2-5 complex. | 31845510 |
2017-11-25 15:03:00 | A positively charged face of NELF-AC is involved in RNA binding, whereas the opposite face of the NELF-AC subcomplex binds NELF-B. NELF-B is predicted to form a HEAT repeat fold, also binds RNA in vivo, and anchors the subunit NELF-E, which is confirmed to bind RNA in vivo. | 27282391 |
2014-02-08 10:47:00 | These studies allow us to position the actions of two new modulators of GR-regulated transactivation, NELF-A and NELF-B, relative to other factors in the overall gene induction sequence. | 24097989 |
2012-11-17 11:04:00 | data show that NELF subunits exhibit highly specific subcellular localizations, such as in NELF bodies or in midbodies, and some shuttle actively between the nucleus and cytoplasm; loss of NELF from cells can lead to enlarged and/or multiple nuclei | 19245807 |
Type | IDs |
---|---|
Synonymous | NELF-A, P/OKcl.15, WHSC2 |
Gene |
UniProtKB-ID:
NELFA_HUMAN,
A0A0C4DFX9_HUMAN
UniprotKB:
Q9H3P2,
A0A0C4DFX9
UniParc:
UPI00004A2565,
UPI0000038D6D,
UPI000016994B
EMBL:
AB044549,
CH471131,
AK126056,
BC002764,
AL132868,
AF131751,
AF101434
Ensembl:
ENSG00000185049
KO:
hsa:7469
|
Nucleutide sequences |
EMBL-CDS:
EAW82546.1,
AAD20034.1,
AAC72982.1,
BAG54283.1,
BAB18651.1,
AAH02764.2
Gene_ORFName:
P/OKcl.15
Ensembl_TRS:
ENST00000382882,
ENST00000542778
|
Protein sequencees |
Ensembl_PRO:
ENSP00000372335,
ENSP00000445757
RefSeq:
XP_016864078.1,
NP_005654.4
|
Others |
UniRef100:
UniRef100_Q9H3P2
UniRef90:
UniRef90_Q9H3P2
UniRef50:
UniRef50_Q9H3P2
UniGene:
Hs.21771
CCDS:
CCDS3358.2
|
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