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74646 Spsb1

74646

Spsb1

splA/ryanodine receptor domain and SOCS box containing 1

protein-coding

Mus musculus

基因描述

Type Description
Definition splA/ryanodine receptor domain and SOCS box containing 1

研究结论

Date Results Publications
2020-03-07 10:51:00 these results establish SSB1/2 as safeguards of B cell development and unveil their differential requirement in immature and mature B lymphocytes 31085591
2017-09-02 11:01:00 Collectively, Ssb1 and Ssb2 control crucial aspects of Hematopoietic stem and progenitor cells function, including proliferation and survival in vivo by resolving replicative stress to maintain genomic stability. 28270450
2015-10-17 11:33:00 SPSB1 negatively regulates the TGF-beta signaling pathway through its interaction with both endogenous and overexpressed TbetaRII (and not TbetaRI) via its Spry domain. 26032413
2015-02-28 12:05:00 Findings define a novel pathway that contributes to breast cancer recurrence and provide evidence implicating SPSB proteins in cancer. 24786206
2013-06-15 12:05:00 Collectively, these results demonstrate essential roles of Ssb1 in embryogenesis, spermatogenesis, and genome stability in vivo. 23408915

名称对应

Type IDs
Synonymous 1110014L01Rik, 4930422J18Rik, AI596360, AI854583, SSB-1, SSB1
Gene
UniProtKB-ID: SPSB1_MOUSE
UniprotKB: Q9D5L7
UniParc: UPI000002476E, UPI00004C95D0
EMBL: AK089767, AF403036, BC046787, AK030417, BC089357, BC057563, AK160081, AK172334, AK040909, AK015181, AK003707
Ensembl: ENSMUSG00000039911
KO: mmu:74646
Nucleutide sequences
EMBL-CDS: BAB29738.1, BAE42952.1, BAC26954.1, AAH57563.1, BAE35613.1, AAL57355.1, BAC30739.1, BAC40957.1, BAC25049.1, AAH46787.1, AAH89357.1
Ensembl_TRS: ENSMUST00000038562, ENSMUST00000105684, ENSMUST00000105685
Protein sequencees
Ensembl_PRO: ENSMUSP00000048969, ENSMUSP00000101310, ENSMUSP00000101309
RefSeq: NP_083311.1, XP_011248647.1, XP_006539297.1, XP_011248646.1
Others
UniRef100: UniRef100_Q9D5L7
UniRef90: UniRef90_Q9D5L7
UniRef50: UniRef50_Q96BD6
UniGene: Mm.30
CCDS: CCDS18966.1

全选

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