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7461 CLIP2

7461

CLIP2

CAP-Gly domain containing linker protein 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition CAP-Gly domain containing linker protein 2

研究结论

Date Results Publications
2020-07-18 11:56:00 CILP-2 is a novel secreted protein and demonstrated that circulating CILP-2 levels were elevated in both IGT and nT2DM subjects and associated with IR. CILP-2 overexpression promoted hepatic IR in HFD-fed mice, increased PEPCK expression and suppressed insulin signaling in hepatocytes. 30896018
2017-05-20 14:29:00 Cross checking with epidemiological estimates and model validation suggests that CLIP2 is a marker of high precision. CLIP2 leaves an imprint in the epidemiological incidence data which is typical for a driver gene. 27729373
2015-10-10 11:07:00 CLIP2 protein expression is elevated in papillary thyroid carcinomas from patients exposed to radioiodine fallout compared with a nonexposed control group. 25284583
2015-09-26 12:16:00 A clear radiation dose-response relationship for the CLIP2 marker expression in post-Chernobyl papillary thyroid carcinomas 25957251
2012-08-25 10:45:00 CLIP2 haploinsufficiency by itself does not lead to the physical or cognitive characteristics of the Williams-Beuren syndrome; GTF2IRD1 and GTF2I are the main genes causing the cognitive defects 22608712

名称对应

Type IDs
Synonymous CLIP, CLIP-115, CYLN2, WBSCR3, WBSCR4, WSCR3, WSCR4
Gene
UniProtKB-ID: CLIP2_HUMAN, A0A140VJG6_HUMAN, A7E2F7_HUMAN
UniprotKB: Q9UDT6, A0A140VJG6, A7E2F7
UniParc: UPI0000E4C8FE, UPI000007061E, UPI0000161590, UPI000020E8EB
EMBL: AF041055, CH471200, AF041059, AF041058, BC150332, AC005015, HM005353, AB006629, AF041057, AF041056
Ensembl: ENSG00000106665
KO: hsa:7461
Nucleutide sequences
EMBL-CDS: BAA22960.2, AAF03524.1, AAB96784.1, EAW69604.1, AEE60953.1, EAW69603.1, AAI50333.1
Gene_ORFName: hCG_18038, hCG_18038
Ensembl_TRS: ENST00000223398, ENST00000361545
Protein sequencees
Ensembl_PRO: ENSP00000223398, ENSP00000355151
RefSeq: NP_003379.4, NP_115797.2
Others
UniRef100: UniRef100_Q9UDT6, UniRef100_A0A140VJG6, UniRef100_A7E2F7
UniRef90: UniRef90_A7E2F7, UniRef90_Q9UDT6
UniRef50: UniRef50_F7G1X1, UniRef50_Q9UDT6
UniGene: Hs.647018
CCDS: CCDS5570.1, CCDS5569.1

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