Type | Description |
---|---|
Definition | NK6 homeobox 3 |
Date | Results | Publications |
---|---|---|
2010-08-30 11:47:00 | Thus, cross-antagonism between Nkx6 and Ptf1a in multipotent progenitors governs the equilibrium between endocrine and acinar cell neogenesis required for normal pancreas development. | 20627083 |
2010-01-21 00:00:00 | Nkx6.3 function is dispensable for CNS development and lead to the proposal that absence of overt defects is due to functional compensation from a related homeodomain transcription factor. | 18586225 |
2010-01-21 00:00:00 | Nkx6.3 shows a remarkably selective expression in a subpopulation of differentiating V2 neurons at caudal hindbrain levels. | 16326147 |
2010-01-21 00:00:00 | Nkx6.3 transcripts localize in the epithelium of the most distal stomach region, the antrum and pylorus; expression in the adult intestine is lower and confined to the proximal duodenum. | 18347062 |
Type | IDs |
---|---|
Synonymous | 9130417I07Rik, Nkx6.3 |
Gene |
UniProtKB-ID:
NKX63_MOUSE,
B2RU70_MOUSE
UniprotKB:
Q3UHX8,
B2RU70
UniParc:
UPI00000237EA
EMBL:
BC140994,
AK018683,
DQ093570,
AK147163
Ensembl:
ENSMUSG00000063672
KO:
mmu:74561
|
Nucleutide sequences |
EMBL-CDS:
BAB31342.1,
AAY98485.1,
BAE27728.1,
AAI40995.1
Ensembl_TRS:
ENSMUST00000071588
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000071517
RefSeq:
NP_083278.1
|
Others |
UniRef100:
UniRef100_Q3UHX8
UniRef90:
UniRef90_Q3UHX8
UniRef50:
UniRef50_Q3UHX8
UniGene:
Mm.290028
CCDS:
CCDS52524.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
24952961 |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron Carol L Thompson , Lydia Ng , Vilas Menon , Salvador Martinez , Chang-Kyu Lee , Katie Glattfelder , Susan M Sunkin , Alex Henry , Christopher Lau , Chinh Dang , Raquel Garcia-Lopez , Almudena Martinez-Ferre , Ana Pombero , John L R Rubenstein , Wayne B Wakeman , John Hohmann , Nick Dee , Andrew J Sodt , Rob Young , Kimberly Smith , Thuc-Nghi Nguyen , Jolene Kidney , Leonard Kuan , Andreas Jeromin , Ajamete Kaykas , Jeremy Miller , Damon Page , Geri Orta , Amy Bernard , Zackery Riley , Simon Smith , Paul Wohnoutka , Michael J Hawrylycz , Luis Puelles , Allan R Jones |
2014-07-16 | - |
22387004 |
Arx is required for normal enteroendocrine cell development in mice and humans. Dev. Biol. Aiping Du , Kyle W McCracken , Erik R Walp , Natalie A Terry , Thomas J Klein , Annie Han , James M Wells , Catherine Lee May |
2012-05-01 |
Isl2,
Arx,
Neurog3,
Cck,
Chga,
Dclk1,
Gast,
Gcg,
Isl1,
Lyz2,
Lyz1,
Muc2,
Neurod1,
Nkx2-2,
Nkx6-1,
Pax4,
Pax6,
Pdx1,
Sct,
Sst,
Tph1,
Ghrl,
Nkx6-3,
ARX
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
20932939 |
Gene Expr. Patterns Yuan Chiang Chung , Yi Ju Tsai , Ting-Ying Shiu , Ya-Yun Sun , Pin-Fang Wang , Chih-Li Chen |
2010-11-01 |
Hoxb2,
Etv5,
Lpxn,
Lmo1,
Krt5,
Lmx1a,
Nr3c2,
Lims1,
D17H6S56E-5,
Foxp2,
Crip3,
Nr0b1,
Aire,
Foxn4,
Alx3,
Alx4,
Nr2f2,
Phox2a,
Zfhx3,
Atp1a1,
Barx2,
Car1,
Nr1i3,
Cdx4,
Vsx2,
Ccr7,
Phc1,
Elf3,
Elf5,
Elk1,
Elk3,
Elk4,
En2,
Epas1,
Nr2f6,
Nr2f1,
Erf,
Erg,
Esr1,
Esx1,
Etv2,
Etv1,
Etv6,
Dmbx1,
Foxh1,
Fhl1,
Fhl2,
Fhl3,
Fhl4,
Foxm1,
Foxd4,
Foxf2,
Gabpa,
Gbx2,
Nr3c1,
Gsx1,
Nkx6-2,
Hesx1,
Foxd3,
Foxg1,
Hhex,
Mnx1,
Hmgb1,
Hmg20b,
Hmgb3,
Nr4a1,
Hmx1,
Hmx2,
Hmx3,
Hnf4a,
Onecut1,
Hoxa1,
Hoxa10,
Hoxa13,
Hoxa2,
Hoxa3,
Hoxa9,
Hoxb1,
Hoxb13,
Hoxb3,
Hoxb5,
Hoxb6,
Hoxb8,
Hoxb9,
Hoxc5,
Hoxc8,
Hoxd12,
Hoxd4,
Hoxd8,
Irf8,
Irf4,
Irx2,
Isl1,
Ajuba,
Krt8,
Lasp1,
Lbx2,
Lef1,
Lhx1
|
20627083 |
Dev. Cell Ashleigh E Schaffer , Kristine K Freude , Shelley B Nelson , Maike Sander |
2010-06-15 |
Amy,
Neurog3,
Gt(ROSA)26Sor,
Nkx6-2,
Ins1,
Ins2,
Nkx6-1,
Pdx1,
Ptf1a,
Sox9,
Klk5,
Nkx6-3
|
19300477 |
Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium. PLoS Genet. Makoto Matsuyama , Shinichi Aizawa , Akihiko Shimono |
2009-03-01 |
Barx1,
Cdh1,
Cdx2,
Dvl2,
Fzd3,
Foxa2,
Hoxa4,
Hoxd13,
Isl1,
Itgb1,
Jun,
Pdx1,
Pitx1,
Prkca,
Prkci,
Prkcz,
Sfrp2,
Sfrp1,
Shh,
Sox2,
Wnt5a,
Sfrp5,
Nkx6-3,
Vangl2
|
18586225 |
Expression and function of Nkx6.3 in vertebrate hindbrain. Brain Res. Brian P Hafler , Michael Y Choi , Ramesh A Shivdasani , David H Rowitch |
2008-07-30 |
Vsx2,
Gata3,
Mnx1,
Lhx3,
Mki67,
Nkx6-1,
Olig2,
Nkx6-3
|
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