| Type | Description |
|---|---|
| Definition | WAS/WASL interacting protein family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:43:00 | PD-L1 promotes tumor growth and progression by activating WIP and beta-catenin signaling pathways and predicts poor prognosis in lung cancer. | 32632098 |
| 2021-02-13 13:28:00 | The Disordered Cellular Multi-Tasker WIP and Its Protein-Protein Interactions: A Structural View. | 32708183 |
| 2019-03-30 11:56:00 | Authors identified WIPF1 as an oncoprotein in PDAC and a direct target of miR-141/miR-200c. They also defined the miR-141/200c-WIPF1-YAP/TAZ as a novel signaling pathway that is involved in the regulation of the invasion and metastasis of human PDAC cells. | 30041660 |
| 2018-12-22 11:36:00 | WIP deficiency should be considered as a cause for autosomal-recessive immunodeficiency | 27742395 |
| 2018-05-05 10:55:00 | WIP residues 454-456 are the major contributor to WASp affinity, and residues 449-451 were found to have the largest effect upon WASp ubiquitylation and, presumably, degradation. | 29215267 |
| Type | IDs |
|---|---|
| Synonymous | PRPL-2, WAS2, WASPIP, WIP |
| Gene |
UniProtKB-ID:
WIPF1_HUMAN,
Q2YDC4_HUMAN,
A0A140VJZ9_HUMAN
UniprotKB:
O43516,
Q2YDC4,
A0A140VJZ9
UniParc:
UPI000013D4BD,
UPI0000D61270,
UPI0000E5A29C,
UPI00005EE229,
UPI0000421E13
EMBL:
HM005539,
BC002914,
BC110288,
BX640870,
X86019,
CH471058,
AC104595,
AF106062,
AF031588,
AC010894
Ensembl:
ENSG00000115935
KO:
hsa:7456
|
| Nucleutide sequences |
EMBL-CDS:
CAE45928.1,
AAC03767.1,
AAD45972.1,
EAX11133.1,
AAY14708.1,
AAH02914.1,
EAX11131.1,
CAA60014.1,
EAX11132.1,
AAI10289.1,
AEE61136.1
Ensembl_TRS:
ENST00000392546,
ENST00000409891,
ENST00000359761,
ENST00000272746,
ENST00000392547
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376330,
ENSP00000386431,
ENSP00000272746,
ENSP00000376329,
ENSP00000352802
RefSeq:
NP_001362766.1,
NP_001362768.1,
NP_001362767.1,
NP_001362763.1,
NP_001362761.1,
NP_003378.3,
NP_001362762.1,
NP_001070737.1,
NP_001362765.1,
NP_001362764.1
|
| Others |
UniRef100:
UniRef100_O43516,
UniRef100_Q2YDC4
UniRef90:
UniRef90_A0A2K5U247,
UniRef90_O43516
UniRef50:
UniRef50_H0XFP4,
UniRef50_O43516
UniGene:
Hs.128067
CCDS:
CCDS2260.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员