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74551 Pck2

74551

Pck2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

protein-coding

Mus musculus

基因描述

Type Description
Definition phosphoenolpyruvate carboxykinase 2 (mitochondrial)

研究结论

Date Results Publications
2020-02-01 10:29:00 Lin28a promotes pathological cardiac hypertrophy and glycolytic reprograming, at least in part, by binding to and stabilizing Pck2 mRNA. 30636447
2017-09-16 10:16:00 Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma 28166201
2016-10-29 12:03:00 Lactate maintains/induces populations of postnatal neuronal progenitors/neural stem cells in a PEPCK-M-dependent manner 25452568
2015-02-21 10:47:00 Amino acid limitation and ER stress inducers, conditions that activate the amino acid response (AAR) and the unfolded protein response (UPR), stimulate PCK2 gene transcription in tumor cell lines. 24973213
2014-02-08 11:49:00 PEPCK-M expression partially rescued defects in lipid metabolism, gluconeogenesis and TCA cycle function impaired by PEPCK-C deletion, while approximately 10% re-expression of PEPCK-C normalized most parameters. 23466304

名称对应

Type IDs
Synonymous 1810010O14Rik, 9130022B02Rik, PEPCK-M
Gene
UniProtKB-ID: PCKGM_MOUSE, A0A0R4J0G0_MOUSE
UniprotKB: Q8BH04, A0A0R4J0G0
UniParc: UPI00000EB990, UPI0000029943
EMBL: AK034927, BC010318, AC159002, AK030501, AK031612
Ensembl: ENSMUSG00000040618
KO: mmu:74551
Nucleutide sequences
EMBL-CDS: AAH10318.1, BAC28883.1, BAC27477.1, BAC26991.1
Ensembl_TRS: ENSMUST00000226519, ENSMUST00000048781
Protein sequencees
Ensembl_PRO: ENSMUSP00000153733, ENSMUSP00000038555
RefSeq: XP_030103944.1, NP_083270.2, XP_030103945.1
Others
UniRef100: UniRef100_Q8BH04
UniRef90: UniRef90_Q16822
UniRef50: UniRef50_P35558
UniGene: Mm.29856, Mm.491140
CCDS: CCDS27114.2

全选

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