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74513 Neto2

74513

Neto2

neuropilin (NRP) and tolloid (TLL)-like 2

protein-coding

Mus musculus

基因描述

Type Description
Definition neuropilin (NRP) and tolloid (TLL)-like 2

研究结论

Date Results Publications
2020-07-11 12:26:00 in cued fear conditioning, Neto2(-/-), but not Neto1(-/-) mice, showed higher fear expression and delayed extinction compared to wild type mice. We established, by in situ hybridization, that Neto2 was expressed in both excitatory and inhibitory neurons throughout the fear circuit including the medial prefrontal cortex, amygdala, and hippocampus. 30770891
2018-05-05 10:05:00 KAR-mediated excitation of interneurons is contingent upon Neto1 because kainate yields comparable effects in Neto2 knockouts and wild-types but fails to excite interneurons or recruit inhibition in Neto1 knockouts. 28854365
2017-08-19 11:05:00 Pain-transducing peripheral sensory neurons of the dorsal root ganglia (DRG) express kainate receptors (KARs), a subfamily of glutamate receptors that modulate neurite outgrowth and regulate glutamate release at the DRG-dorsal horn synapse. 28235897
2016-08-27 12:10:00 These results establish critical roles for Neto auxiliary subunits controlling Kainate receptor properties and synaptic incorporation. 26720915
2013-06-15 11:33:00 Neto2 interacts with the scaffolding protein GRIP and regulates synaptic abundance of kainate receptors. 23236500

名称对应

Type IDs
Synonymous 5530601C23Rik, AI854825, BTCL2
Gene
UniProtKB-ID: NETO2_MOUSE
UniprotKB: Q8BNJ6
UniParc: UPI000045812E, UPI00000EB1CA
EMBL: AK081462, AY138991, BC151050, AK083512
Ensembl: ENSMUSG00000036902
KO: mmu:74513
Nucleutide sequences
EMBL-CDS: AAN38319.1, AAI51051.1, BAC38938.1, BAC38225.1
Ensembl_TRS: ENSMUST00000216286, ENSMUST00000109686
Protein sequencees
Ensembl_PRO: ENSMUSP00000150062, ENSMUSP00000105308
RefSeq: XP_036010232.1, XP_036010231.1, NP_001344216.1, NP_001344217.1, NP_001074793.1, XP_030099678.1, XP_036010230.1, XP_006531500.1
Others
UniRef100: UniRef100_Q8BNJ6
UniRef90: UniRef90_Q8BNJ6
UniRef50: UniRef50_Q8BNJ6
UniGene: Mm.126079
CCDS: CCDS40423.1, CCDS90432.1

全选

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