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74442 Sgms2

74442

Sgms2

sphingomyelin synthase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition sphingomyelin synthase 2

研究结论

Date Results Publications
2021-03-20 13:33:00 Sphingomyelin synthase 2 loss suppresses steatosis but exacerbates fibrosis in the liver of mice fed with choline-deficient, L-amino acid-defined, high-fat diet. 33059919
2020-12-19 13:39:00 Sphingomyelin Synthase 2 Inhibition Ameliorates Cerebral Ischemic Through Reducing the Recruitment of Toll-Like Receptor 4 to Lipid Rafts. 31718447
2020-08-01 14:01:00 Sgms2-knockout and wild-type control mice were exposed to cigarette smoke for 6 months.Chronic cigarette smoke reduces SGMS activity and gene expression in mouse lungs. Sgms2-deficient mice have enhanced airway and tissue resistance after chronic cigarette smoke exposure, but similar degrees of emphysema to wild-type. Sgms2(-/-) mice had greater AKT phosphorylation, peribronchial collagen deposition and protease activity. 31517509
2020-07-11 12:17:00 Investigated role of sphingomyelin synthase 1 (SMS1) and sphingomyelin synthase 2 (SMS2) in osteoblast differentiation in order to better understand the role SMS1 and SMS2 play in skeletal development. 31847800
2020-02-15 11:51:00 These results suggest that SMS2 regulates osteoclast differentiation by inducing RANKL expression via RXRalpha. 31597904

名称对应

Type IDs
Synonymous 4933405A16Rik, 5133401H06Rik, AI854299
Gene
UniProtKB-ID: SMS2_MOUSE
UniprotKB: Q9D4B1
UniParc: UPI0000029F24
EMBL: BC117782, AK016659
Ensembl: ENSMUSG00000116143, ENSMUSG00000050931
KO: mmu:74442
Nucleutide sequences
EMBL-CDS: BAB30364.2, AAI17783.1
Ensembl_TRS: ENSMUST00000090246, ENSMUST00000230673
Protein sequencees
Ensembl_PRO: ENSMUSP00000087713, ENSMUSP00000155182
RefSeq: NP_001366513.1, XP_011238551.1, NP_001366511.1, NP_083219.2, NP_001366512.1, NP_001366516.1, NP_001366514.1, NP_001366515.1
Others
UniRef100: UniRef100_Q9D4B1
UniRef90: UniRef90_Q9D4B1
UniRef50: UniRef50_Q9D4B1
UniGene: Mm.273360
CCDS: CCDS17843.1

全选

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