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7443 VRK1

7443

VRK1

VRK serine/threonine kinase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition VRK serine/threonine kinase 1

研究结论

Date Results Publications
2021-04-03 13:30:00 Phosphorylation of vaccinia-related kinase 1 at threonine 386 transduces glucose stress signal in human liver cells. 32266931
2020-10-31 13:14:00 VRK1 functional insufficiency due to alterations in protein stability or kinase activity of human VRK1 pathogenic variants implicated in neuromotor syndromes. 31527692
2020-09-26 13:06:00 Motor neuron diseases caused by a novel VRK1 variant - A genotype/phenotype study. 31560180
2020-04-18 10:12:00 VRK1 takes part in the regulatory function of Ras-PI3K pathway on H2A(T120ph) 31810390
2020-04-11 12:46:00 Findings support vaccinia-related kinase 1 as a causative gene for adult-onset distal hereditary motor neuropathy, and indicate its relevance for evaluation of individuals with similar motor impairment. 31837156

名称对应

Type IDs
Synonymous PCH1, PCH1A
Gene
UniProtKB-ID: VRK1_HUMAN
UniprotKB: Q99986
UniParc: UPI0000073867
EMBL: BC103761, AB000449, BC112075, BC113510
Ensembl: ENSG00000100749
KO: hsa:7443
Nucleutide sequences
EMBL-CDS: AAI13511.1, AAI12076.1, BAA19108.1, AAI03762.1
Ensembl_TRS: ENST00000216639
Protein sequencees
Ensembl_PRO: ENSP00000216639
RefSeq: XP_011535434.1, NP_003375.1, XP_016877115.1, XP_016877114.1, XP_016877113.1, XP_006720310.1
Others
UniRef100: UniRef100_Q99986
UniRef90: UniRef90_Q99986
UniRef50: UniRef50_Q99986
UniGene: Hs.422662
CCDS: CCDS9947.1

全选

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研究热度

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