| Type | Description |
|---|---|
| Definition | C-type lectin domain family 16, member A |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:59:00 | Study found that lncRNA Malat1 expression is distinctly regulated in differentially activated macrophages in that it is upregulated in LPS-treated and downregulated in IL-4-treated cells. Malat1 regulates the expression of Clec16a, which is required for the proinflammatory activation of macrophages. Data demonstrate that Malat1 is involved in pulmonary pathogeneses in association with aberrant macrophage activation. | 30676324 |
| 2020-01-11 11:01:00 | CLEC16A restrains secretory functions including cytokine release and cytotoxicity, and a delicate balance of CLEC16A is needed for NK cell function and homeostasis. | 30774629 |
| 2019-03-02 10:52:00 | regulates splenocyte and NK cell function in part through MEK signaling | 30226884 |
| 2017-01-28 11:20:00 | Study provides evidence that Clec16a plays a key role in the survival of Purkinje cells and in the degradative function or clearance of autolysosomes. | 26987296 |
| 2016-03-05 10:07:00 | CLEC16A associations in common variable immunodeficiency disorder represent the first robust evidence of non-HLA associations in this immunodeficiency condition. | 25891430 |
| Type | IDs |
|---|---|
| Synonymous | 4932416N17Rik, curt, mKIAA0350 |
| Gene |
UniProtKB-ID:
CL16A_MOUSE
UniprotKB:
Q80U30
UniParc:
UPI00000E90CC,
UPI00004EAFF1,
UPI00005AD062,
UPI0000EF8891,
UPI00005B2704
EMBL:
AC122352,
BC138907,
AC154430,
BC138909,
AK155314,
AK170754,
AK122255,
CT010583,
AK156927,
AK016529
Ensembl:
ENSMUSG00000068663
KO:
mmu:74374
|
| Nucleutide sequences |
EMBL-CDS:
BAE33899.1,
BAC65537.1,
AAI38908.1,
BAE33184.1,
BAC25487.1,
AAI38910.1,
BAE42005.1
Ensembl_TRS:
ENSMUST00000155633,
ENSMUST00000115827,
ENSMUST00000038145,
ENSMUST00000066345,
ENSMUST00000115823
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000111489,
ENSMUSP00000040267,
ENSMUSP00000123189,
ENSMUSP00000065423,
ENSMUSP00000111493
RefSeq:
NP_001191158.1,
XP_006522728.1,
XP_036016059.1,
XP_017172637.1,
XP_006522726.1,
NP_808230.2,
XP_017172638.1,
XP_011244329.1,
XP_006522723.1,
XP_036016057.1,
XP_030105172.1,
XP_006522724.1,
XP_006522725.1,
XP_030105173.1,
XP_030105171.1,
XP_036016058.1,
XP_006522727.1,
XP_036016056.1
|
| Others |
UniRef100:
UniRef100_Q80U30
UniRef90:
UniRef90_Q80U30
UniRef50:
UniRef50_Q80U30
UniGene:
Mm.159176
CCDS:
CCDS57018.1,
CCDS37253.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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