| Type | Description |
|---|---|
| Definition | HOP homeobox |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:00:00 | Knock-out of Hopx disrupts stemness and quiescence of hematopoietic stem cells in mice. | 32533098 |
| 2019-12-21 11:26:00 | HOPX expression in cultured ATII cells increased over culture time. HOPX expression was increased in AECs from bleomycin-instilled mouse lungs in vivo. Small interfering RNA-based knockdown of Hopx resulted in suppressing ATII-ATI trans-differentiation and activating cellular proliferation in vitro. | 30154568 |
| 2019-09-21 10:50:00 | These results support an early priming of neural stem cells (NSCs) for the genesis of defined cell types depending on their spatial location in the subventricular zone and identify HOPX as a marker of a subpopulation primed toward astrocytic fates. | 30174314 |
| 2019-02-16 10:51:00 | Hopx is required and sufficient, respectively, for basal radial glial cells abundance as found in the developing gyrencephalic neocortex. | 30266827 |
| 2016-06-04 10:18:00 | Analysis of the hematopoietic stem/progenitor cell pool in Hopx-/- mice demonstrated significantly reduced cell frequencies and impaired engraftment in competitive repopulation assays, thus providing functional validation of this positional candidate gene | 26050929 |
| Type | IDs |
|---|---|
| Synonymous | 1110018K11Rik, 1200015P04Rik, 2300002F06Rik, AI848177, AW490897, Cameo, Hdop, Hod, Hop, Ob1, Obl, Toto |
| Gene |
UniProtKB-ID:
HOP_MOUSE
UniprotKB:
Q8R1H0
UniParc:
UPI00000269D6
EMBL:
AK004798,
AK008297,
BC024546,
AK003784,
AF492704,
AK008439,
AF536202,
AK009007,
AF492703,
AF534182
Ensembl:
ENSMUSG00000059325
KO:
mmu:74318
|
| Nucleutide sequences |
EMBL-CDS:
BAC25097.1,
AAM46824.1,
AAM46823.1,
BAC25235.1,
AAN05634.1,
AAH24546.1,
BAC25219.1,
AAN16320.1,
BAC25054.1,
BAC25214.1
Ensembl_TRS:
ENSMUST00000081964,
ENSMUST00000113453,
ENSMUST00000120827
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080630,
ENSMUSP00000109080,
ENSMUSP00000113295
RefSeq:
NP_001153372.1,
XP_036021457.1,
NP_783199.1,
NP_001153373.1
|
| Others |
UniRef100:
UniRef100_Q8R1H0
UniRef90:
UniRef90_Q8R1H0
UniRef50:
UniRef50_Q8R1H0
UniGene:
Mm.181852,
Mm.478741
CCDS:
CCDS39120.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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