| Type | Description |
|---|---|
| Definition | filamin binding LIM protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 10:04:00 | Findings indicate that tightly regulated expression of migfilin is essential for neuronal development and that FBLIM1 disruption may be related to the phenotypes associated with ASD and related neurodevelopmental disorders. | 29114925 |
| 2016-02-13 12:17:00 | Suggest migfilin regulates cardiac hypertrophy in transverse aortic constriction. | 25852081 |
| 2014-02-15 10:45:00 | C-terminal LIM domains of migfilin dictate its focal adhesion localization, and these domains mediate an interaction with kindlin in vitro and in cells, demonstrating that kindlin is important for normal migfilin dynamics. | 24165133 |
| 2012-08-25 11:31:00 | results identify FBLP-1 as a key regulator of bone homeostasis and suggest that FBLP-1 functions in this process through modulating both the intrinsic properties of OB/BMSCs (i.e., BMSC-extracellular matrix adhesion and migration | 22556421 |
| 2012-08-11 10:24:00 | This study demonistrated that a molecular mechanism whereby FlnA loss impaired G2 to M phase entry, leading to cell cycle prolongation, compromised neural progenitor proliferation, and reduced brain size. | 22649246 |
| Type | IDs |
|---|---|
| Synonymous | 2410043F08Rik, Cal, Fblp1, Gt10, migfilin, migfilin(s) |
| Gene |
UniProtKB-ID:
FBLI1_MOUSE
UniprotKB:
Q71FD7
UniParc:
UPI00000279AE
EMBL:
AK170151,
AL670446,
AF513359,
AK170440,
AK154680,
CH466615,
BC004777
Ensembl:
ENSMUSG00000006219
KO:
mmu:74202
|
| Nucleutide sequences |
EMBL-CDS:
AAQ08090.1,
BAE32761.1,
EDL13383.1,
AAH04777.1,
BAE41798.1,
EDL13384.1,
BAE41598.1,
EDL13382.1,
EDL13381.1,
EDL13386.1,
EDL13385.1
Ensembl_TRS:
ENSMUST00000105785,
ENSMUST00000105784,
ENSMUST00000006381
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000006381,
ENSMUSP00000101410,
ENSMUSP00000101411
RefSeq:
XP_006539279.1,
NP_001365888.1,
XP_006539278.1,
NP_001365887.1,
XP_006539276.1,
NP_598515.3,
NP_001156728.1,
XP_006539277.1,
XP_030109701.1
|
| Others |
UniRef100:
UniRef100_Q71FD7
UniRef90:
UniRef90_Q71FD7
UniRef50:
UniRef50_Q8WUP2
UniGene:
Mm.490327
CCDS:
CCDS18876.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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